Description

1,2-Dipalmitoyl-Sn-Glycerol 3-((((4-Azido-2-Nitrophenyl)Amino)Ethyl)Phosphate) is a specialized, photoactivatable phospholipid derivative designed for advanced biochemical research and bioconjugation. This compound is critical for researchers developing novel lipid-based probes, drug delivery systems, and membrane biology tools due to its unique ability to form covalent crosslinks upon UV irradiation. It is primarily utilized by pharmaceutical R&D teams, academic research laboratories, and biotechnology companies focused on liposome engineering, cell surface labeling, and targeted therapeutic applications.

Application

• Photoaffinity Labeling in Membrane Biology: Used to covalently tag and study lipid-protein interactions, membrane receptors, and enzyme active sites upon UV light activation.
• Functionalized Liposome Production: Serves as a key component for creating targeted drug delivery vesicles (e.g., for cancer therapy) by enabling surface conjugation of antibodies, peptides, or other targeting ligands.
• Bioconjugation & Probe Synthesis: Acts as a versatile building block for synthesizing fluorescent, radioactive, or affinity-tagged lipid probes for imaging and diagnostic assays.
• Model Membrane Systems: Incorporated into artificial lipid bilayers (e.g., supported lipid bilayers, liposomes) to study membrane dynamics, fusion, and signaling.
• Material Science & Surface Chemistry: Employed to create bio-functionalized surfaces and coatings for biosensors, microarrays, and implantable medical devices.
• Crosslinking Studies: Facilitates the investigation of spatial relationships and molecular proximities within complex lipid assemblies or between lipids and other biomolecules.

Basic Information

Product Name	1,2-Dipalmitoyl-Sn-Glycerol 3-((((4-Azido-2-Nitrophenyl)Amino)Ethyl)Phosphate)
CAS No.	110457-62-0
Molecular Formula	C43H76N5O10P
Molecular Weight	854.06 g/mol
Synonyms	1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(4-azido-2-nitrophenyl); DPPE-ANP; N-(4-Azido-2-nitrophenyl)-1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine; ANP-DPPE; Photoactivatable DPPE; 1,2-Dihexadecanoyl-sn-glycero-3-phosphoethanolamine-N-(4-azido-2-nitrophenyl); N-4-Azido-2-nitrophenylphosphatidylethanolamine (dipalmitoyl); Azidophenylnitro DPPE
EINECS	Contact for details

Quality Control

Our 1,2-Dipalmitoyl-Sn-Glycerol 3-((((4-Azido-2-Nitrophenyl)Amino)Ethyl)Phosphate) is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and critical impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and advanced material science research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange powder or solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in chloroform, DMSO; slightly soluble in ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.