Description

2'-n-Methyl-8-Methoxychlortetracycline is a chemically modified derivative of the classic broad-spectrum antibiotic, chlortetracycline, designed to enhance specific pharmacological properties. This compound is of significant interest for advanced pharmaceutical research and development, particularly in the study of next-generation tetracycline-class antibiotics. It is primarily utilized by research institutions, pharmaceutical manufacturers, and biotechnology companies engaged in antimicrobial drug discovery and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the research and synthesis of novel tetracycline-class antibiotics with potentially improved efficacy or reduced resistance.
• Antimicrobial Research: Used as a reference standard or active compound in microbiological studies to investigate structure-activity relationships (SAR) against a range of bacterial pathogens.
• Biochemical Research: Employed in laboratory settings to study bacterial protein synthesis inhibition mechanisms and the effects of chemical modifications on antibiotic activity.
• Veterinary Medicine Development: Investigated for potential applications in developing advanced treatments for bacterial infections in animals.
• Academic & Institutional Research: A critical material for universities and research institutes focusing on medicinal chemistry and antibiotic discovery programs.

Basic Information

Product Name	2'-n-Methyl-8-Methoxychlortetracycline
CAS No.	110298-65-2
Molecular Formula	C23H24ClN2O9
Molecular Weight	507.90 g/mol
Synonyms	2'-N-Methyl-8-methoxychlortetracycline; 8-Methoxy-2'-N-methylchlortetracycline; 2'-N-Methyl-8-O-methylchlortetracycline; N-Methyl-8-methoxychlortetracycline; 2'-N-Methyl-8-methoxy-7-chlorotetracycline; 7-Chloro-2'-N-methyl-8-methoxytetracycline; A derivative of Aureomycin
EINECS	Contact for details

Quality Control

Our 2'-n-Methyl-8-Methoxychlortetracycline is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency suitable for research applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity determination and spectroscopic methods for structural confirmation. A Certificate of Analysis (COA) detailing specific results is provided with every shipment to guarantee traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.