Description

8-Methoxychlortetracycline is a chemically modified derivative of the classic broad-spectrum antibiotic, chlortetracycline. This compound is valued in research and development for its altered biological activity and physicochemical properties, offering a pathway to explore new therapeutic agents and biochemical tools. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of fine chemicals for the synthesis of novel tetracycline analogs.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the synthesis and study of novel tetracycline-class antibiotics with potentially improved efficacy or reduced resistance.
• Biochemical Research: Used as a tool compound to investigate bacterial protein synthesis inhibition mechanisms and structure-activity relationships (SAR) within the tetracycline family.
• Fine Chemical Synthesis: Acts as a specialized building block for the production of more complex, targeted antimicrobial agents or labeled compounds for diagnostic purposes.
• Reference Standard: Employed in analytical laboratories for method development, validation, and quality control testing of related pharmaceutical substances.

Basic Information

Product Name	8-Methoxychlortetracycline
CAS No.	110298-63-0
Molecular Formula	C23H23ClN2O9
Molecular Weight	506.89 g/mol
Synonyms	8-Methoxy-7-chlorotetracycline; 7-Chloro-8-methoxytetracycline; 8-Methoxy-chlortetracycline; 8-O-Methylchlorotetracycline; NSC 113029
EINECS	Contact for details

Quality Control

Our 8-Methoxychlortetracycline is produced and handled under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided, which includes results from HPLC, NMR, and other relevant spectroscopic methods. We support custom synthesis and can tailor specifications to meet specific research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.