Description

Monoaspartyl Chlorin E6 is a chemically modified chlorin derivative, a key intermediate and active pharmaceutical ingredient (API) in advanced photodynamic therapy (PDT) and photodynamic diagnosis (PDD) applications. Its value lies in its optimized photophysical properties, offering a superior balance between photosensitizing efficacy and tissue selectivity for targeted treatments. This compound is essential for pharmaceutical manufacturers and research institutions developing next-generation cancer therapeutics, dermatological treatments, and diagnostic imaging agents.

Application

• Pharmaceutical API: Core active ingredient in formulated photodynamic therapy (PDT) drugs for treating various cancers, including skin, esophageal, and lung cancers.
• Photodynamic Diagnosis (PDD): Used as a fluorescent contrast agent for the real-time visualization and demarcation of malignant tissues during surgical procedures.
• Dermatology: Key component in topical formulations for treating actinic keratosis, psoriasis, and other skin conditions via targeted light activation.
• Biomedical Research: Vital tool in preclinical studies for investigating mechanisms of photodynamic action, drug delivery systems, and new light-based therapies.
• Chemical Synthesis: Serves as a crucial synthetic intermediate for producing more complex, second-generation photosensitizers with enhanced properties.
• Veterinary Medicine: Applied in PDT treatments for certain cancers and conditions in companion animals.

Basic Information

Product Name	Monoaspartyl Chlorin E6
CAS No.	110230-98-3
Molecular Formula	C46H58N6O10
Molecular Weight	854.99 g/mol
Synonyms	N-Aspartyl chlorin e6; MACE; Talaporfin sodium precursor; Laserphyrin intermediate; LS 11; Mono-L-aspartyl chlorin e6; Chlorin e6 monoaspartylamide; Photosensitizer LS11; Aspartyl chlorin
EINECS	Contact for details

Quality Control

Our Monoaspartyl Chlorin E6 is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, UV-Vis), to ensure it meets stringent specifications for pharmaceutical use. Certificates of Analysis (COA) detailing all test results are provided with every shipment. Production can adhere to cGMP guidelines for API manufacture upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term stability, storage at 2-8°C is recommended. The container should be kept in a dry environment to minimize the risk of moisture uptake.

Specification

Item	Specification
Appearance	Dark green to brownish-green powder
Identification (HPLC)	Conforms to reference standard
Identification (UV-Vis)	Conforms to reference standard
Purity (HPLC, Area %)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0% Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.