Description

n-(2-Aminopropyl)Maleimide is a specialized bifunctional chemical intermediate featuring both a reactive maleimide group and a primary amine. This compound matters for its unique ability to facilitate selective conjugation and cross-linking reactions, enabling the precise modification of biomolecules and polymers. It is primarily needed by researchers and manufacturers in the pharmaceutical, bioconjugation, and advanced materials sectors for developing targeted drug delivery systems, diagnostic reagents, and functional polymers.

Application

• Bioconjugation Reagent: For site-specific labeling of antibodies, proteins, and peptides to create antibody-drug conjugates (ADCs) or diagnostic probes.
• Polymer Modification: As a cross-linker or functional monomer in the synthesis of smart hydrogels, responsive polymers, and surface coatings.
• Pharmaceutical Intermediate: In the research and development of novel small-molecule therapeutics and prodrugs.
• Material Science: For the functionalization of nanoparticles, dendrimers, and other nanomaterials to impart specific chemical handles.
• Biochemical Research: A key tool in studying protein interactions, enzyme mechanisms, and cellular processes through covalent modification.
• Diagnostic Assay Development: Used to immobilize or tag biomolecules on biosensors and microarray platforms.

Basic Information

Product Name	n-(2-Aminopropyl)Maleimide
CAS No.	110008-25-8
Molecular Formula	C7H10N2O2
Molecular Weight	154.17 g/mol
Synonyms	1-(2-Aminopropyl)-1H-pyrrole-2,5-dione; 2,5-Pyrrolidinedione, 1-(2-aminopropyl)-; Maleimide, N-(2-aminopropyl)-; N-(2-Aminopropyl)maleimide; 2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)propan-1-amine; APM; Aminopropyl maleimide
EINECS	Contact for details

Quality Control

Our n-(2-Aminopropyl)Maleimide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets high-purity standards suitable for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere when possible and allowed to reach room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.