Description

(6S)-5,6,7,8-Tetrahydro-L-Biopterin Sulfate is a high-purity, reduced form of the essential cofactor L-Biopterin, critical for enzymatic reactions involving aromatic amino acid hydroxylases. This compound is vital for research and development in biochemistry and pharmaceutical sciences, particularly in studying metabolic pathways and enzyme function. It is primarily sought by researchers and manufacturers in the life sciences, pharmaceutical intermediates, and diagnostic reagent sectors for its role in neurotransmitter synthesis and metabolic studies.

Application

• Biochemical Research: Essential cofactor for studying phenylalanine, tyrosine, and tryptophan hydroxylases in neurotransmitter biosynthesis pathways.
• Pharmaceutical Intermediates: Used in the synthesis and development of compounds targeting metabolic disorders and neurological conditions.
• Diagnostic Reagents: A key component in enzymatic assay kits for the detection and quantification of amino acids and related metabolites.
• Enzyme Activity Studies: Serves as a critical reagent for in vitro assays to determine the activity and kinetics of pterin-dependent enzymes.
• Cell Culture & Neuroscience: Applied in cell-based research models to investigate cellular metabolism and neuronal function.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for HPLC and other chromatographic methods.

Basic Information

Product Name	(6S)-5,6,7,8-Tetrahydro-L-Biopterin Sulfate
CAS No.	109784-74-9
Molecular Formula	C9H15N5O3 • xH2SO4
Molecular Weight	315.33 g/mol (Free base)
Synonyms	6R-L-erythro-5,6,7,8-Tetrahydrobiopterin Sulfate; (6S)-BH4 Sulfate; Tetrahydrobiopterin Sulfate; Sapropterin Sulfate; L-BH4 Sulfate; 5,6,7,8-Tetrahydro-L-Biopterin Sulfate; (6R)-5,6,7,8-Tetrahydro-L-Biopterin Sulfate (enantiomer); 2-Amino-6-[(1R,2S)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydropteridin-4(1H)-one Sulfate
EINECS	Contact for details

Quality Control

Our (6S)-5,6,7,8-Tetrahydro-L-Biopterin Sulfate is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade specifications suitable for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.