Description

Riboflavin 5'-Phosphorothioate is a chemically modified derivative of riboflavin (vitamin B2), where a sulfur atom replaces an oxygen atom in the phosphate group. This structural modification is significant for its role as a biochemical tool in the study of flavoenzyme mechanisms and as a potential precursor for novel cofactors. It is primarily required by research institutions and pharmaceutical developers focused on enzymology, metabolic pathway analysis, and the development of advanced diagnostic assays.

Application

• Biochemical Research: Used as a substrate analog and mechanistic probe in studies of flavin-dependent enzymes, such as dehydrogenases and oxidoreductases.
• Pharmaceutical Development: Serves as a key intermediate or reference standard in the research and development of novel therapeutics targeting metabolic disorders.
• Diagnostic Reagent Manufacturing: Employed in the formulation of specialized diagnostic kits for clinical and research laboratories to measure specific enzymatic activities.
• Nutraceutical Research: Investigated for its potential bioactivity and stability as a modified form of vitamin B2 in advanced nutritional science studies.
• Enzyme Engineering: Utilized in directed evolution and protein engineering projects to create enzymes with altered cofactor specificity or enhanced catalytic properties.

Basic Information

Product Name	Riboflavin 5'-Phosphorothioate
CAS No.	109637-87-8
Molecular Formula	C17H21N4O9P1S1
Molecular Weight	504.41 g/mol
Synonyms	Riboflavin 5'-Thiophosphate; Flavin Mononucleotide (FMN) Thioanalog; Vitamin B2 5'-Phosphorothioate; 5'-O-Phosphorothioylriboflavin; 7,8-Dimethyl-10-ribitylisoalloxazine 5'-Phosphorothioate; Riboflavin 5'-(Thiomonophosphate); FMN-S
EINECS	Contact for details

Quality Control

Our Riboflavin 5'-Phosphorothioate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC/UV)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.