Description

Boc-Gln-Arg-Arg-Amc Acetate Salt is a synthetic, protected peptide substrate specifically designed for biochemical research and diagnostic applications. This compound is of critical importance for studying and quantifying the activity of specific proteolytic enzymes, such as furin and other proprotein convertases. It is primarily needed by researchers and manufacturers in the fields of pharmaceutical development, proteomics, and clinical diagnostics for high-throughput screening and assay development.

Application

• Enzyme Activity Assays: As a fluorogenic substrate for the continuous, sensitive measurement of furin and related proprotein convertase activity.
• Drug Discovery Screening: Used in high-throughput screening (HTS) platforms to identify and characterize novel enzyme inhibitors for therapeutic development.
• Biochemical Research: A key tool for investigating protease function, specificity, and kinetics in cellular signaling and protein processing pathways.
• Diagnostic Kit Development: Incorporated into diagnostic assays for detecting and monitoring diseases associated with dysregulated protease activity.
• Quality Control in Biologics: Employed in the biopharmaceutical industry to monitor and ensure the consistency of recombinant protein production processes.

Basic Information

Product Name	Boc-Gln-Arg-Arg-Amc Acetate Salt
CAS No.	109376-05-8
Molecular Formula	C34H58N14O10 • xC2H4O2
Molecular Weight	822.93 g/mol (free base)
Synonyms	Boc-Gln-Arg-Arg-AMC Acetate; t-Butyloxycarbonyl-Glutamine-Arginine-Arginine-7-Amino-4-Methylcoumarin Acetate; Boc-Q-R-R-AMC Acetate; Furin Substrate Boc-Gln-Arg-Arg-AMC; Proprotein Convertase Substrate; Fluorogenic Peptide Substrate 109376-05-8; Boc-Gln-Arg-Arg-AFC (related analog); t-BOC-Gln-Arg-Arg-AMC
EINECS	Contact for details

Quality Control

Our Boc-Gln-Arg-Arg-Amc Acetate Salt is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for sensitive research and diagnostic applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and functional activity validation. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Functional Activity	Conforms to reference standard

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.