Description

Biotinamidocaproyl Hydrazide is a biotin derivative featuring a reactive hydrazide group, making it a versatile intermediate for bioconjugation and labeling applications. Its primary value lies in its ability to serve as a key linker for attaching biotin to various biomolecules, enabling detection and purification via the strong biotin-streptavidin interaction. This compound is essential for researchers and manufacturers in the life sciences, pharmaceutical development, and diagnostic reagent industries.

Application

• Bioconjugation Reagent: Used as a critical linker for covalently attaching biotin to antibodies, proteins, peptides, and oligonucleotides.
• Diagnostic Kit Manufacturing: A key component in the production of ELISA, lateral flow assays, and other immunoassays for signal amplification.
• Affinity Chromatography: Functionalizes resins and surfaces for the purification of biomolecules using streptavidin/avidin capture.
• Cell Surface Labeling: Facilitates the tagging of cell surface proteins and carbohydrates for flow cytometry and microscopy studies.
• Drug Delivery Systems: Employed in the development of targeted therapeutic conjugates and nanoparticle functionalization.
• Biomaterial Modification: Used to introduce biotin groups onto polymers, hydrogels, and other materials for biomedical research.

Basic Information

Product Name	Biotinamidocaproyl Hydrazide
CAS No.	109276-34-8
Molecular Formula	C16H30N4O2S
Molecular Weight	342.50 g/mol
Synonyms	Biotin-LC-hydrazide; Biotinamidocaproic Acid Hydrazide; Biotinamidocaproyl Hydrazine; N-Biotinyl-6-aminocaproic Acid Hydrazide; 6-[(5-[(3aS,4S,6aR)-2-Oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoyl)amino]hexanoic Acid Hydrazide; Biotinyl-ε-aminocaproyl-hydrazide; (+)-Biotin-6-amidocaproic Hydrazide
EINECS	Contact for details

Quality Control

Our Biotinamidocaproyl Hydrazide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive research and production applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support development under cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.