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1,2-Dipentadecanoyl-Sn-Glycero-3-Phosphoethanolamine CAS NO 109032-52-2


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CAS No.:109032-52-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,2-Dipentadecanoyl-Sn-Glycero-3-Phosphoethanolamine is a synthetic, saturated phospholipid belonging to the phosphatidylethanolamine (PE) class. This high-purity lipid is a critical building block for constructing advanced lipid-based delivery systems and biomimetic membranes. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require precisely defined lipid components. The compound is supplied under strict quality control to ensure batch-to-batch consistency for sensitive applications.

Application

  • Liposome and Nanoparticle Formulation: A key structural phospholipid for creating stable liposomal drug delivery vehicles, mRNA-LNPs (lipid nanoparticles), and other nanocarriers.
  • Biomembrane Research: Used to create model lipid bilayers and vesicles (e.g., giant unilamellar vesicles, GUVs) for studying membrane biophysics, protein-lipid interactions, and cellular processes.
  • Drug Delivery Excipient: Functions as a fusogenic lipid component in formulations designed for enhanced cellular uptake and endosomal escape of therapeutic cargo.
  • Diagnostic Reagent Development: Serves as a substrate or membrane component in diagnostic assays and biosensors requiring controlled surface chemistry.
  • Cosmetic Actives Carrier: Employed in high-end cosmetic formulations to encapsulate and improve the delivery of active ingredients to the skin.
  • Bioconjugation & Surface Modification: The primary amine on the phosphoethanolamine headgroup provides a site for chemical conjugation with targeting ligands, dyes, or other functional molecules.

Basic Information

Product Name 1,2-Dipentadecanoyl-Sn-Glycero-3-Phosphoethanolamine
CAS No. 109032-52-2
Molecular Formula C37H74NO8P
Molecular Weight 692.0 g/mol (approx.)
Synonyms 1,2-Dipentadecanoyl-sn-glycero-3-phosphoethanolamine; DPPE (C15:0); 1,2-Di(pentadecanoyl)-sn-glycero-3-phosphoethanolamine; PE(15:0/15:0); Phosphatidylethanolamine(30:0); 3-sn-Phosphatidylethanolamine, 1,2-dipentadecanoyl-; 1,2-Di(pentadecanoyl)-sn-glycero-3-phosphorylethanolamine
EINECS Contact for details

Quality Control

Our 1,2-Dipentadecanoyl-Sn-Glycero-3-Phosphoethanolamine is manufactured under a cGMP-compliant quality management system to ensure the highest standards of purity and traceability. Each batch undergoes comprehensive analytical characterization, including HPLC for purity and identity confirmation and mass spectrometry for structural verification. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item Specification
Appearance White to off-white powder or solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Melting Point Contact for details
Water Content (KF) ≤ 1.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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