Description

Benzeneacetic Acid, -α--Ethyl-4-(2-Methylpropyl)-, Labeled With Tritium (9Ci) is a high-specific-activity, tritium-labeled derivative of a key phenylacetic acid compound, essential for advanced metabolic and pharmacokinetic research. This product provides a critical tool for scientists requiring precise, sensitive detection and quantification in complex biological systems. It is primarily utilized by researchers in the pharmaceutical, agrochemical, and life science sectors for applications such as drug metabolism studies (ADME), receptor binding assays, and environmental fate analysis.

Application

• Drug Metabolism and Pharmacokinetics (DMPK/ADME) Studies: Tracing the absorption, distribution, metabolism, and excretion of novel pharmaceutical compounds.
• Receptor Binding and Enzyme Inhibition Assays: Used as a radioligand to investigate target engagement, affinity, and mechanism of action.
• Metabolic Pathway Elucidation: Mapping biochemical transformation pathways in vivo and in vitro to identify active metabolites.
• Environmental Fate and Ecotoxicology Research: Tracking the degradation, bioaccumulation, and transport of chemical substances in environmental models.
• Analytical Method Development: Serving as an internal standard or tracer in LC-MS/MS, HPLC, and scintillation counting techniques for method validation.
• Agrochemical Research: Studying the uptake, translocation, and metabolism of pesticides and herbicides in plants.

Basic Information

Product Name	Benzeneacetic Acid, -α--Ethyl-4-(2-Methylpropyl)-, Labeled With Tritium (9Ci)
CAS No.	108789-32-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	α-Ethyl-4-isobutylphenylacetic acid, Tritium-labeled; 2-(4-Isobutylphenyl)butyric acid, Tritiated; [³H]-2-(4-Isobutylphenyl)butanoic acid; Tritium-labeled Ibuprofen precursor analog; Radiolabeled phenylacetic acid derivative; [³H]-α-Ethyl-4-(2-methylpropyl)benzeneacetic acid
EINECS	Contact for details

Quality Control

Every batch of this radiolabeled compound is produced and analyzed under strict quality protocols to ensure high radiochemical purity and specific activity. Quality assurance includes verification by analytical techniques such as HPLC with radiometric detection. Certificates of Analysis (COA) detailing specific activity, radiochemical purity, chemical purity, and solvent composition are provided with each shipment to support regulatory compliance and research integrity.

Storage

Preserve in a tightly closed container, protected from light. Store at or below -20°C in the original solvent as specified on the label. Due to its high volatility and radioactive nature, store in a dedicated, appropriately shielded freezer or area in accordance with local radiation safety regulations. Allow to reach room temperature in a controlled fume hood before opening.

Specification

Item	Specification
Appearance	Clear colorless to slightly yellow solution
Specific Activity	~9 Ci/mmol (Contact for exact value)
Radiochemical Purity (HPLC)	≥ 95%
Chemical Purity (HPLC)	≥ 98%
Solvent	Ethanol, Toluene, or as specified
Concentration	1.0 mCi/mL (Typical, customizable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.