Description

Udp-3-o-(3-Hydroxymyristoyl)-n-Acetylglucosamine is a key biochemical intermediate, specifically a lipid A precursor, involved in the biosynthesis of bacterial lipopolysaccharides. This compound is of significant value for research into bacterial cell wall assembly, antibiotic resistance mechanisms, and the development of novel anti-infective agents. It is primarily needed by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in microbiology, immunology, and drug discovery programs.

Application

• Biochemical Research: Critical substrate for studying the enzymatic pathways of lipid A biosynthesis in Gram-negative bacteria.
• Drug Discovery: Used as a reference standard and tool compound in high-throughput screening for inhibitors of bacterial membrane synthesis.
• Enzyme Assay Development: Serves as a specific substrate for assays targeting enzymes like LpxA and other acyltransferases in the Raetz pathway.
• Vaccine Adjuvant Research: Investigated for its role in modulating immune responses due to its structural relationship to lipid A, a potent TLR4 agonist.
• Metabolic Pathway Analysis: Utilized in tracer studies and metabolic flux analysis to understand bacterial physiology under stress.
• Academic & Pharmaceutical R&D: A fundamental reagent for basic science and applied research into sepsis, inflammation, and novel antimicrobial strategies.

Basic Information

Product Name	Udp-3-o-(3-Hydroxymyristoyl)-n-Acetylglucosamine
CAS No.	108636-29-9
Molecular Formula	C33H56N3O19P2
Molecular Weight	884.76 g/mol
Synonyms	UDP-3-O-[(3R)-3-Hydroxytetradecanoyl]-N-acetyl-α-D-glucosamine; UDP-3-O-(3-Hydroxymyristoyl)-GlcNAc; Lipid A Precursor IV-A; UDP-3-O-(3-Hydroxymyristoyl)-N-acetylglucosamine; UDP-3-O-(3R-Hydroxymyristoyl)-α-D-N-acetylglucosamine; 3-O-[(3R)-3-Hydroxytetradecanoyl]-N-acetyl-α-D-glucosaminyl dihydrogen diphosphate; Uridine 5'-[3-O-[(3R)-3-hydroxytetradecanoyl]-2-(acetylamino)-2-deoxy-α-D-glucopyranosyl] diphosphate
EINECS	Contact for details

Quality Control

Our Udp-3-o-(3-Hydroxymyristoyl)-n-Acetylglucosamine is produced under stringent conditions suitable for research applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure consistency and reliability. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.