Description

Elastase Substrate Iv, Colorimetric is a specialized biochemical reagent designed for the detection and quantification of elastase enzyme activity. This compound serves as a critical tool in enzymatic research and diagnostic assay development, offering a colorimetric readout for precise measurement. It is essential for researchers and quality control laboratories in the pharmaceutical, biotechnology, and life sciences sectors who require reliable substrates for protease analysis and inhibitor screening.

Application

• Enzymatic Assay Development: Primary substrate for in vitro colorimetric assays measuring human leukocyte elastase (HLE) or pancreatic elastase activity.
• Drug Discovery & Screening: Used in high-throughput screening (HTS) platforms to identify and characterize novel elastase inhibitors for therapeutic applications.
• Biomedical Research: Facilitates the study of elastase's role in inflammatory diseases, such as chronic obstructive pulmonary disease (COPD), cystic fibrosis, and atherosclerosis.
• Diagnostic Kit Manufacturing: A key component in the formulation of clinical diagnostic kits for assessing elastase levels in biological samples.
• Biochemical Reagent Production: Supplied as a high-purity raw material for manufacturers of research-grade biochemical kits and reagents.
• Quality Control (QC) Testing: Employed in QC laboratories to validate the activity of recombinant elastase enzymes or to test the potency of anti-elastase formulations.

Basic Information

Product Name	Elastase Substrate Iv, Colorimetric
CAS No.	108392-27-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	N-Methoxysuccinyl-Ala-Ala-Pro-Val p-Nitroanilide; MeOSuc-AAPV-pNA; Elastase Substrate IV; Leukocyte Elastase Substrate; Suc(OMe)-Ala-Ala-Pro-Val-pNA; Elastase Chromogenic Substrate IV; Human Leukocyte Elastase (HLE) Substrate; AAPV-pNA
EINECS	Contact for details

Quality Control

Our Elastase Substrate Iv, Colorimetric is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay results, and physical characteristics is provided with every shipment to guarantee traceability and performance consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term stability, consider storage under desiccant.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content	≤ 1.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in water
Assay (Enzymatic)	≥ 95% of theoretical activity

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.