Description

Aurachin A CAS NO 108354-15-0 is a specialized quinoline alkaloid compound of significant interest in biochemical and pharmacological research. This compound serves as a potent and selective inhibitor of the cytochrome bc1 complex (Complex III) in the mitochondrial electron transport chain. It is primarily utilized by researchers and developers in the life sciences sector for studying cellular respiration, oxidative stress, and for the discovery of novel antimicrobial and antiparasitic agents.

Application

• Biochemical Research: A key tool for investigating mitochondrial function, electron transport chain dynamics, and mechanisms of oxidative phosphorylation.
• Antimicrobial Agent Development: Serves as a lead compound or reference standard in the research and development of new antibiotics targeting bacterial respiration.
• Antiparasitic Studies: Used in protozoology research to study and develop treatments for parasites like Plasmodium (malaria) and Toxoplasma gondii.
• Enzyme Inhibition Studies: Acts as a specific inhibitor for the cytochrome bc1 complex, facilitating studies on enzyme kinetics and inhibitor binding sites.
• Cell Biology & Metabolism: Employed in cellular assays to model mitochondrial dysfunction, study ATP production, and explore links to diseases.
• Reference Standard: Used as a high-purity analytical standard in pharmaceutical quality control and method validation for related compounds.

Basic Information

Product Name	Aurachin A
CAS No.	108354-15-0
Molecular Formula	C₂₅H₃₅NO₃
Molecular Weight	397.55 g/mol
Synonyms	Aurachin A; 2-Heptyl-4-hydroxyquinoline N-oxide; 2-Heptyl-4-hydroxyquinoline 1-oxide; 4-Hydroxy-2-heptylquinoline 1-oxide; Cytochrome bc1 Complex Inhibitor; Respiratory Chain Inhibitor; Complex III Inhibitor
EINECS	Contact for details

Quality Control

Every batch of Aurachin A is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency for research applications. Our standard grade meets high-purity standards suitable for biochemical and in-vitro use, with comprehensive characterization via HPLC, NMR, and MS. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to prevent oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.