Description

1,2-Dihexadecanoyl-Sn-Glycero-3-Phospho[n-Hexadecanoyl]Ethanolamine Ammonium Salt is a high-purity, synthetic phospholipid derivative, specifically a saturated phosphatidylethanolamine (PE) analog. This compound is critical for creating stable, well-defined lipid bilayers and vesicles, serving as a fundamental building block in advanced biomimetic research and formulation science. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require precise control over membrane composition and properties.

Application

• Liposome & Nanoparticle Formulation: A key structural component for creating stable, uniform liposomes used in drug delivery systems, mRNA vaccines, and diagnostic agents.
• Biomembrane & Model Membrane Studies: Used to construct supported lipid bilayers (SLBs) and giant unilamellar vesicles (GUVs) for studying membrane protein interactions, permeability, and cell signaling mechanisms.
• Pharmaceutical Excipient: Employed as a functional excipient to enhance the stability and bioavailability of active pharmaceutical ingredients (APIs) in various dosage forms.
• Biophysical Research: Essential for calorimetry (DSC), spectroscopy, and microscopy studies to understand lipid phase behavior, fusion, and membrane dynamics.
• Cosmetic & Dermal Delivery Systems: Incorporated into nanocarriers and creams for the targeted and sustained release of active compounds in cosmetic and topical pharmaceutical products.
• Diagnostic Reagent Manufacturing: Used in the production of reagents and assays that rely on membrane-based recognition and signal amplification.

Basic Information

Product Name	1,2-Dihexadecanoyl-Sn-Glycero-3-Phospho[n-Hexadecanoyl]Ethanolamine Ammonium Salt
CAS No.	108321-22-8
Molecular Formula	C73H147N2O9P
Molecular Weight	1251.92 g/mol
Synonyms	1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-hexadecanoyl (Ammonium Salt); N-Palmitoyl-DPPE; N-Hexadecanoyl-DPPE; DPPE-C16; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(palmitoyl); N-Acyl DPPE (C16:0); PE(16:0/16:0/16:0); Saturated Phosphatidylethanolamine Derivative; Ammonium Salt of N-Palmitoyl-DPPE
EINECS	Contact for details

Quality Control

Our 1,2-Dihexadecanoyl-Sn-Glycero-3-Phospho[n-Hexadecanoyl]Ethanolamine Ammonium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, TLC for lipid profile analysis, and NMR for structural verification. We provide full traceability and Certificates of Analysis (COA) detailing all specifications. Production can adhere to cGMP guidelines for applications requiring the highest level of quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. For short-term use, the product may be stored at 2-8°C. This material is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (TLC)	Single spot, conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Phase Transition Temperature (DSC)	Reported value

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.