Description

1,2-Distearoyl-Sn-Glycero-3-Phosphatidic Acid, Sodium Salt is a high-purity, synthetic phospholipid derivative, specifically a phosphatidic acid (PA) in its sodium salt form. This compound serves as a critical building block and functional excipient in advanced pharmaceutical and cosmetic formulations. It is essential for researchers and manufacturers in the liposome, drug delivery, and biomimetic membrane sectors who require precise and reliable lipid components.

Application

• Liposome and Nanoparticle Formulation: A key anionic lipid component for creating stable, charged liposomal carriers for targeted drug and gene delivery systems.
• Biomimetic Membrane Research: Used in model membrane studies to investigate lipid-protein interactions, membrane fusion, and signaling processes involving phosphatidic acid.
• Cosmetic Actives Delivery: Functions as an emulsifier and penetration enhancer in high-end skincare products for improved delivery of active ingredients.
• Pharmaceutical Excipient: Employed as a stabilizer and component in complex injectable formulations and sustained-release platforms.
• Biochemical Reagent: Serves as a substrate or standard in enzymatic assays for phospholipase D (PLD) and other lipid-metabolizing enzymes.
• Crystal Engineering & Material Science: Investigated for its self-assembly properties in the development of novel lipid-based nanomaterials and thin films.

Basic Information

Product Name	1,2-Distearoyl-Sn-Glycero-3-Phosphatidic Acid, Sodium Salt
CAS No.	108321-18-2
Molecular Formula	C39H74NaO8P
Molecular Weight	724.96 g/mol
Synonyms	DSPA (Na); 1,2-Distearoyl-sn-glycerol-3-phosphate sodium salt; PA(18:0/18:0) sodium salt; Phosphatidic acid (di18:0) sodium salt; Sodium 1,2-distearoyl-sn-glycero-3-phosphate; 1,2-Di-O-stearoyl-sn-glycerol-3-phosphate sodium salt; DSPA-Na; L-α-Phosphatidic acid, disteroyl, sodium salt
EINECS	Contact for details

Quality Control

Our 1,2-Distearoyl-Sn-Glycero-3-Phosphatidic Acid, Sodium Salt is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, TLC for identity and impurities, and NMR for structural confirmation. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with rigorous R&D and cGMP-grade material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This material is hygroscopic (moisture-sensitive). For long-term storage, keep under an inert atmosphere (argon or nitrogen). Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR & NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Solubility	Soluble in chloroform, methanol; forms dispersions in water
Loss on Drying	≤ 2.0 %
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Biological Testing (where applicable)	Endotoxin & Bioburden upon request

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.