Description

Piperazine-N,N'-Bis(2-Hydroxypropanesulphonic Acid) Disodium Salt is a high-purity, water-soluble organic buffer agent and chelator. This compound is valued for its excellent buffering capacity in the physiological pH range and its ability to complex metal ions, making it a critical component in formulations requiring precise pH control and stability. It is primarily utilized by manufacturers in the pharmaceutical, biotechnology, and diagnostic reagent industries for applications such as cell culture media, biochemical assays, and stabilizing sensitive biological molecules.

Application

• Biochemical & Diagnostic Reagents: As a key buffering agent in enzyme assays, electrophoresis buffers, and diagnostic kit formulations.
• Pharmaceutical Formulations: Used in the development and stabilization of injectable drugs, vaccines, and protein-based therapeutics.
• Cell Culture Media: Provides a stable pH environment for the growth of mammalian and bacterial cells in bioproduction and research.
• Molecular Biology: A component of lysis buffers, hybridization buffers, and PCR master mixes to maintain optimal reaction conditions.
• Chelation & Metal Ion Control: Acts as a sequestrant for trace metal ions that can catalyze degradation in sensitive chemical and biological systems.
• Industrial Processes: Employed in water treatment and specific chemical synthesis processes where pH stabilization is required.

Basic Information

Product Name	Piperazine-N,N'-Bis(2-Hydroxypropanesulphonic Acid) Disodium Salt
CAS No.	108321-07-9
Molecular Formula	C10H18N2Na2O10S2
Molecular Weight	436.36 g/mol
Synonyms	PIPES Disodium Salt; 1,4-Piperazinediethanesulfonic Acid Disodium Salt; Piperazine-1,4-bis(2-ethanesulfonic acid) Disodium Salt; PIPES Na2; Disodium PIPES; Good's Buffer PIPES Disodium Salt; 1,4-Piperazinebis(ethanesulfonic acid) Disodium Salt; PIPES Buffer Salt
EINECS	Contact for details

Quality Control

Our Piperazine-N,N'-Bis(2-Hydroxypropanesulphonic Acid) Disodium Salt is manufactured under a strict quality management system. Each batch is tested to ensure it meets high-purity standards suitable for research and industrial applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed to prevent absorption of atmospheric moisture, which can affect product quality and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
pH (1% Solution)	6.5 - 7.5
Water Content (KF)	≤ 2.0%
Heavy Metals (as Pb)	≤ 10 ppm
Residue on Ignition	≤ 0.1%
Solubility (in Water)	Clear, colorless solution

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.