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1-Nonadecanoyl-2-Hydroxy-Sn-Glycero-3-Phosphocholine CAS NO 108273-88-7


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CAS No.:108273-88-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-Nonadecanoyl-2-Hydroxy-Sn-Glycero-3-Phosphocholine is a high-purity synthetic phospholipid, specifically a lysophosphatidylcholine (LPC) derivative with a defined 19-carbon fatty acyl chain. This compound is of significant value for its role as a critical biochemical standard and a versatile building block in advanced lipid research and formulation. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require precise lipid components for membrane studies, drug delivery systems, and diagnostic applications.

Application

  • Biochemical Research & Standard: Serves as a high-purity reference standard for analytical methods (HPLC, MS) and for studying lysophospholipid metabolism, signaling pathways, and membrane biophysics.
  • Lipidomics & Metabolomics: Used as a critical internal standard or calibrant in mass spectrometry-based lipidomic profiling to quantify endogenous LPC species in biological samples.
  • Pharmaceutical Excipient & Drug Delivery: Investigated as a component in liposomal and nanoparticle formulations to enhance drug solubility, stability, and targeted cellular uptake.
  • Cell Culture & Membrane Biology: Employed in model membrane systems (e.g., vesicles, supported lipid bilayers) to study the effects of specific lysophospholipids on membrane fluidity, curvature, and protein interactions.
  • Diagnostic Reagent Development: Utilized in the development of enzymatic assays and diagnostic kits that measure phospholipase activity or specific lipid biomarkers.
  • Cosmetic & Dermal Formulations: Acts as a bioactive ingredient or emulsifier in high-end cosmetic products aimed at skin barrier repair and moisturization.

Basic Information

Product Name 1-Nonadecanoyl-2-Hydroxy-Sn-Glycero-3-Phosphocholine
CAS No. 108273-88-7
Molecular Formula C27H56NO7P
Molecular Weight 537.71 g/mol
Synonyms LysoPC(19:0); 1-Nonadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine; LPC(19:0); 1-Nonadecanoyl-sn-glycero-3-phosphocholine; Lysophosphatidylcholine(19:0); 2-Hydroxy-1-nonadecanoyl-sn-glycero-3-phosphocholine; sn-Glycero-3-phosphocholine 1-nonadecanoate; 1-Monononadecanoylphosphatidylcholine
EINECS Contact for details

Quality Control

Our 1-Nonadecanoyl-2-Hydroxy-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques including NMR, Mass Spectrometry, and HPLC to ensure structural identity and high chemical purity. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item Specification
Appearance White to off-white solid or waxy solid
Identification (NMR) Conforms to structure
Identification (MS) Conforms to structure
Purity (HPLC) ≥ 95% (Area %)
Assay ≥ 98% (by weight)
Solubility Soluble in chloroform, methanol, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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