Description

(-)-Noe'S Reagent CAS NO 108031-79-4 is a high-purity, enantiomerically pure chiral reagent widely used in asymmetric synthesis. This compound is valued for its role as a powerful chiral auxiliary and ligand in catalytic reactions, enabling the production of optically active intermediates with high stereoselectivity. It is essential for research and development in the pharmaceutical, agrochemical, and fine chemical industries, where precise control over molecular chirality is critical.

Application

• As a chiral ligand in asymmetric metal-catalyzed reactions, including hydrogenation and C-C bond formation.
• As a chiral auxiliary for the stereoselective synthesis of complex pharmaceutical intermediates and active pharmaceutical ingredients (APIs).
• In the preparation of enantiomerically pure agrochemicals and specialty fine chemicals.
• For academic and industrial research in organic methodology development and catalysis.
• In the synthesis of natural products and other complex molecules requiring high enantiomeric excess (ee).
• As a reference standard for analytical method development and quality control in chiral separation techniques.

Basic Information

Item	Detail
Product Name	(-)-Noe'S Reagent
CAS No.	108031-79-4
Molecular Formula	C₁₃H₂₁NO₄
Molecular Weight	255.31 g/mol
Synonyms	(-)-Norephedrine derivative; (1R,2S)-(-)-N-Methylephedrine; (1R,2S)-(-)-N-Methylephedrine; (-)-N-Methylephedrine; L-N-Methylephedrine; (1R,2S)-2-(Methylamino)-1-phenylpropan-1-ol; Noe's Chiral Auxiliary; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our (-)-Noe'S Reagent is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) documenting identity, purity, and enantiomeric excess are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.