Description

Formycin Triphosphate-Terbium Complex is a specialized nucleotide-lanthanide coordination complex, identified by CAS NO 107870-98-4. This compound is engineered to serve as a highly sensitive luminescent probe, leveraging the unique photophysical properties of terbium ions for advanced detection and analysis. It is primarily utilized by researchers and developers in the fields of molecular diagnostics, biochemical assay development, and high-throughput screening where precise, time-resolved fluorescence detection is critical.

Application

• Time-Resolved Fluorescence (TRF) Assays: Acts as a luminescent label for nucleotides in immunoassays and hybridization assays, offering superior signal-to-noise ratios.
• Molecular Beacon Probes: Used in the design of sensitive probes for the real-time detection of specific DNA or RNA sequences.
• Enzyme Activity Studies: Serves as a substrate or product analog for kinases, polymerases, and other nucleotide-processing enzymes, enabling continuous monitoring of enzymatic activity.
• Drug Discovery Screening: Employed in high-throughput screening platforms to identify inhibitors or activators of nucleic acid-related targets.
• Biophysical Research: Utilized in studies of protein-nucleic acid interactions and structural dynamics due to its long-lived luminescence and sensitivity to the local environment.
• Diagnostic Kit Development: A key component in the development of sensitive in-vitro diagnostic (IVD) kits for clinical and research laboratories.

Basic Information

Product Name	Formycin Triphosphate-Terbium Complex
CAS No.	107870-98-4
Molecular Formula	C11H14N4O13P3Tb (Representative)
Molecular Weight	Contact for details
Synonyms	FTP-Tb Complex; Formycin 5'-Triphosphate Terbium Chelate; Tb3+-FormycinTP; Terbium(III)-Formycin Triphosphate; 1-β-D-Ribofuranosyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine 5'-(tetrahydrogen triphosphate) terbium complex; Luminescent Formycin Nucleotide; TRF-Labeled Formycin Triphosphate; Nucleotide-Lanthanide Conjugate
EINECS	Contact for details

Quality Control

Our Formycin Triphosphate-Terbium Complex is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, spectrophotometry for concentration and complex integrity, and luminescence lifetime measurement to ensure optimal performance. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term stability, store under inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or solid
Identification (HPLC/UV)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Assay (Spectrophotometry)	90% - 110% of labeled concentration
Terbium Content (ICP-MS)	1:1 molar ratio (Nucleotide:Tb), ±10%
Luminescence Lifetime	Contact for details
Water Content (KF)	≤ 5.0%
Solubility	Soluble in aqueous buffers (e.g., Tris, HEPES)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.