Description

(R)-(1-Phenylethyl)Succinate is a high-purity chiral intermediate of significant importance in asymmetric synthesis. This compound matters because it serves as a versatile building block for the production of optically active pharmaceuticals and fine chemicals. Industries that need it include pharmaceutical R&D, contract manufacturing organizations (CMOs), and specialty chemical producers focused on developing enantiomerically pure active pharmaceutical ingredients (APIs).

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A key precursor for the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Catalyst Ligand Preparation: Used in the development and synthesis of novel chiral ligands for asymmetric hydrogenation and other catalytic transformations.
• Resolution Agent: Employed in the chiral resolution of racemic mixtures of amines, alcohols, and other acids due to its stable, separable diastereomeric derivatives.
• Fine Chemical and Flavor/Fragrance Intermediate: Utilized in the synthesis of complex, high-value aroma chemicals and specialty esters requiring specific stereochemistry.
• Academic and Industrial Research: Serves as a standard or starting material in methodological development for new stereoselective reactions.

Basic Information

Product Name	(R)-(1-Phenylethyl)Succinate
CAS No.	107832-33-7
Molecular Formula	C12H14O4
Molecular Weight	222.24 g/mol
Synonyms	(R)-1-Phenylethyl hydrogen succinate; (R)-α-Methylbenzyl hydrogen succinate; Succinic acid mono-[(1R)-1-phenylethyl] ester; (R)-Mono(1-phenylethyl) succinate; (R)-PEHS; (R)-H-Phe-O-Suc-OH (contextual); Butanedioic acid, mono[(1R)-1-phenylethyl] ester
EINECS	Contact for details

Quality Control

Our (R)-(1-Phenylethyl)Succinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with exacting customer specifications and industry standards. Certificates of Analysis (COA) with detailed chromatographic data are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.