Description

3β-Glycocholic Acid is a conjugated bile acid, a key biochemical formed from the amide linkage of cholic acid with glycine. This compound is essential for the emulsification and absorption of dietary fats and fat-soluble vitamins in the intestine. It serves as a critical reference standard and raw material in pharmaceutical research, diagnostic reagent manufacturing, and biochemical studies. Industries requiring high-purity biochemical intermediates, such as pharmaceutical development, clinical diagnostics, and life science research, rely on consistent supplies of this material.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of bile acid profiles in drug development and quality control (QC/QA).
• Diagnostic Reagent Manufacturing: A key component in the production of enzymatic assay kits for liver function tests and metabolic disorder diagnostics.
• Biochemical Research: Employed in studies of lipid metabolism, hepatobiliary function, and the role of bile acids in gut microbiota interactions.
• Cell Culture & Media Supplement: Used in specific mammalian cell culture applications to mimic physiological conditions or study bile acid transport.
• Metabolite Standard for LC-MS/MS: Serves as a critical calibration standard in advanced analytical techniques like liquid chromatography-mass spectrometry for clinical and research laboratories.

Basic Information

Product Name	3β-Glycocholic Acid
CAS No.	107589-98-0
Molecular Formula	C₂₆H₄₃NO₆
Molecular Weight	465.63 g/mol
Synonyms	Glycocholic Acid; 3β-Glycocholate; N-[(3β,5β,7α,12α)-3,7,12-Trihydroxy-24-oxocholan-24-yl]glycine; Glycocholsäure; Cholylglycine; Glycocholic acid (VAN); Glycocholate sodium; Taurochenodeoxycholic acid impurity C (EP)
EINECS	Contact for details

Quality Control

Our 3β-Glycocholic Acid is manufactured under a quality management system and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Specifications are designed to meet the stringent requirements of pharmaceutical reference standard and diagnostic reagent applications. A comprehensive Certificate of Analysis (COA) detailing purity by HPLC, identification by IR, and specific impurity profiles is provided with each batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Specific Optical Rotation	Contact for details
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.