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R-(+)-1-(9-Fluorenyl)Ethanol CAS NO 107474-78-2
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CAS No.:107474-78-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
R-(+)-1-(9-Fluorenyl)Ethanol is a high-purity chiral alcohol derivative of fluorene, characterized by its specific (R)-(+) enantiomeric configuration. This compound is a critical chiral building block and resolving agent in asymmetric synthesis, valued for its ability to impart stereoselectivity in complex chemical transformations. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require enantiomerically pure intermediates for the development of active ingredients and specialty chemicals.
Application
- Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drugs.
- Asymmetric Catalyst Ligand Precursor: Used in the preparation of chiral ligands for transition metal catalysts employed in enantioselective hydrogenation, cross-coupling, and other catalytic reactions.
- Chiral Resolving Agent: Employed for the optical resolution of racemic mixtures of acids, amines, and other alcohols via diastereomeric salt or ester formation.
- Agrochemical Synthesis: Acts as a building block for creating chiral herbicides, fungicides, and plant growth regulators with enhanced biological activity and environmental profile.
- Material Science Research: Utilized in the development of chiral liquid crystals, polymers, and organic semiconductors for optoelectronic applications.
- Academic & R&D Laboratories: A valuable reagent for methodological development in organic synthesis and stereochemistry studies.
Basic Information
| Product Name | R-(+)-1-(9-Fluorenyl)Ethanol |
| CAS No. | 107474-78-2 |
| Molecular Formula | C₁₅H₁₄O |
| Molecular Weight | 210.27 g/mol |
| Synonyms | (R)-(+)-1-(9H-Fluoren-9-yl)ethanol; (R)-9-Fluorenemethanol; (R)-9-Fluorenylmethanol; (R)-(+)-9-Fluorenylmethyl alcohol; (R)-9-Fluoren-9-ylmethanol; (R)-α-Fluoren-9-ylmethyl alcohol; (R)-1-(9H-Fluoren-9-yl)ethan-1-ol; (R)-(+)-1-Fluoren-9-ylethanol |
| EINECS | Contact for details |
Quality Control
Our R-(+)-1-(9-Fluorenyl)Ethanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high enantiomeric excess (e.e.) and chemical purity, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity and stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Enantiomeric Excess (Chiral HPLC) | ≥ 99.0% |
| Melting Point | Contact for details |
| Specific Rotation [α]₂₀D | Contact for details |
| Heavy Metals | < 10 ppm |
| Residue on Ignition | < 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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