Description

5,20-Dihydroxy-6,8,11,14-Eicosatetraenoic Acid is a specialized eicosanoid derivative, a key intermediate in the study of lipoxygenase and cytochrome P450 metabolic pathways. This compound is valued for its role as a biochemical tool in advanced research and development, particularly in elucidating inflammatory and cellular signaling mechanisms. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on metabolic and pharmacological studies.

Application

• Biochemical Research Standard: Used as a reference standard in analytical methods (HPLC, LC-MS) for the quantification of eicosanoid metabolites in biological samples.
• Enzymology Studies: Serves as a substrate or product analog in studies involving lipoxygenase (LOX) and cytochrome P450 (CYP) enzyme activity and inhibition.
• Cell Signaling Pathway Investigation: Employed in cellular assays to probe the biological effects and signaling roles of dihydroxy-eicosatetraenoic acids (diHETEs) in inflammation and immune response.
• Pharmaceutical Development: Acts as a critical intermediate or reference compound in the discovery and development of novel anti-inflammatory or metabolic disorder therapeutics.
• Metabolite Identification: Used in mass spectrometry laboratories for the structural confirmation and identification of novel oxylipin metabolites.

Basic Information

Product Name	5,20-Dihydroxy-6,8,11,14-Eicosatetraenoic Acid
CAS No.	107373-23-9
Molecular Formula	C₂₀H₃₂O₄
Molecular Weight	336.47 g/mol
Synonyms	5,20-DiHETE; (5S,20S)-Dihydroxy-6E,8Z,11Z,14Z-eicosatetraenoic Acid; 5,20-Dihydroxyeicosatetraenoic Acid; 5,20-DiHETrE; 5,20-Dihydroxy-6,8,11,14-eicosatetraenoate; 5,20-DiHETE (6E,8Z,11Z,14Z); 5(S),20(S)-DiHETE
EINECS	Contact for details

Quality Control

Every batch of 5,20-Dihydroxy-6,8,11,14-Eicosatetraenoic Acid is manufactured and analyzed under strict quality management systems to ensure high purity and batch-to-batch consistency for research applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity confirmation, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.