Description

2-(12-n-Dansylaminododecanoyl)-1-Myristoylglycerol CAS NO 107141-09-3 is a specialized fluorescently-labeled diacylglycerol (DAG) analog, a critical tool compound in biochemical research. Its core value lies in the dansyl fluorophore, which enables sensitive detection and visualization of lipid-protein interactions and enzymatic activity. This product is essential for researchers in cell signaling, lipid metabolism, and membrane biology who require high-purity, well-characterized probes for advanced studies.

Application

• Biochemical Research Probe: Used as a fluorescent substrate or tracer in studies of diacylglycerol kinases (DGKs), phospholipases, and other lipid-metabolizing enzymes.
• Cell Signaling Studies: Investigates Protein Kinase C (PKC) activation and translocation mechanisms due to its structural similarity to native DAG second messengers.
• Lipid-Protein Interaction Analysis: Employed in fluorescence polarization (FP), fluorescence resonance energy transfer (FRET), and other biophysical assays to study binding dynamics.
• Membrane Biology: Serves as a tool to visualize and quantify lipid dynamics, trafficking, and domain formation within artificial or cellular membranes.
• High-Throughput Screening (HTS): Acts as a key reagent in assay development for drug discovery programs targeting lipid signaling pathways.
• Academic & Pharmaceutical R&D: Fundamental research in universities and drug discovery efforts in biotech/pharma companies focused on metabolic and signaling disorders.

Basic Information

Item	Detail
Product Name	2-(12-n-Dansylaminododecanoyl)-1-Myristoylglycerol
CAS No.	107141-09-3
Molecular Formula	C₄₆H₇₇N₃O₇S
Molecular Weight	828.19 g/mol
Synonyms	1-Myristoyl-2-[12-[(5-dimethylaminonaphthalene-1-sulfonyl)amino]dodecanoyl]-sn-glycerol; DAG(Dansyl); Fluorescent Diacylglycerol Analog; sn-1-Myristoyl-2-(12-dansylaminododecanoyl)glycerol; 2-(12-(Dansylamino)dodecanoyl)-1-myristoylglycerol; Dansyl-C12-DAG; 1-Myristoyl-2-(N-dansyl-aminododecanoyl)-sn-glycerol
EINECS	Contact for details

Quality Control

Every batch of 2-(12-n-Dansylaminododecanoyl)-1-Myristoylglycerol is synthesized and purified under controlled conditions to ensure the highest standards of identity, purity, and performance. Our quality assurance protocol includes comprehensive analytical characterization. Certificates of Analysis (COA) detailing lot-specific results for purity, identity, and fluorescence properties are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. Allow the product to equilibrate to room temperature before opening to minimize moisture condensation. Solutions prepared in appropriate solvents (e.g., DMSO, chloroform) should be aliquoted and stored under inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange solid or film
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Solubility	Soluble in DMSO, chloroform, DMF
Fluorescence Properties	Excitation ~340 nm, Emission ~520 nm (solvent dependent)
Storage Condition	-20°C, desiccated, protected from light

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.