Description

1-Dodecyl-2-Eicosyl-Glycero-3-Phosphocholine is a synthetic, high-purity phospholipid belonging to the phosphatidylcholine class, characterized by its specific long-chain alkyl substituents. This compound is a critical component for constructing advanced lipid-based delivery systems and biomimetic membranes due to its unique structural properties. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require precise lipid components for liposomal drug delivery, cell membrane modeling, and diagnostic applications.

Application

• Liposomal Drug Formulation: A key structural lipid for creating stable, long-circulating liposomes for targeted delivery of anticancer drugs, vaccines, and nucleic acids (e.g., mRNA).
• Biomimetic Membrane Research: Used in the construction of model cell membranes (e.g., supported lipid bilayers, vesicles) for studying membrane protein interactions, permeability, and cellular processes.
• Diagnostic Reagents: Serves as a component in diagnostic kits and assays that utilize liposome-based signal amplification or cell lysis.
• Cosmetic & Dermal Delivery: Incorporated into nanocarrier systems (niosomes, transfersomes) for enhanced skin penetration and delivery of active ingredients in cosmetic and topical pharmaceutical products.
• Cell Culture & Transfection: Used as a supplement in specialized cell culture media or as a component in lipid-based transfection reagents for introducing genetic material into cells.
• Material Science: Acts as a surface modifier or a building block for creating functionalized nanomaterials and smart coatings with biocompatible properties.

Basic Information

Product Name	1-Dodecyl-2-Eicosyl-Glycero-3-Phosphocholine
CAS No.	106689-19-4
Molecular Formula	C40H82NO8P
Molecular Weight	736.05 g/mol
Synonyms	1-Lauroyl-2-Arachidoyl-sn-Glycero-3-Phosphocholine; DLaPC; 12:0-20:0 PC; 1-Dodecanoyl-2-Eicosanoyl-sn-Glycero-3-Phosphocholine; PC(12:0/20:0); Phosphatidylcholine(12:0/20:0); Lauryl-Arachidoyl Phosphatidylcholine; LAPC
EINECS	Contact for details

Quality Control

Our 1-Dodecyl-2-Eicosyl-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for research and GMP-grade applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical quality attributes. We support compliance with relevant pharmaceutical and regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This material is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to prevent condensation and moisture uptake. For short-term use, store desiccated at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm
Peroxide Value	< 1.0 meq/kg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.