Description

Demethylchlortetracycline is a semi-synthetic derivative of the broad-spectrum tetracycline class of antibiotics. This compound is valued for its potent antibacterial activity, particularly against a wide range of Gram-positive and Gram-negative bacteria. It is a critical intermediate and active pharmaceutical ingredient (API) primarily required by the pharmaceutical industry for research, development, and manufacturing of advanced antibiotic formulations.

Application

• Pharmaceutical API: Used as an active pharmaceutical ingredient in the formulation of antibiotic drugs.
• Veterinary Medicine: Employed in the development of antibacterial treatments for livestock and companion animals.
• Biomedical Research: Serves as a key reference standard and tool compound in microbiological and pharmacological studies.
• Antibiotic Resistance Studies: Utilized in research to understand bacterial resistance mechanisms and develop new therapeutic strategies.
• Intermediate for Derivatives: Acts as a chemical precursor for the synthesis of more specialized tetracycline analogs.

Basic Information

Product Name	Demethylchlortetracycline
CAS No.	106276-91-9
Molecular Formula	C₂₁H₂₁ClN₂O₈
Molecular Weight	464.86 g/mol
Synonyms	Demethylchlorotetracycline; 6-Demethyl-7-chlorotetracycline; DMCT; Declomycin (as a derivative); 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-7-chloro-2-naphthacenecarboxamide; Antibiotic L 696; NSC-528986
EINECS	Contact for details

Quality Control

Our Demethylchlortetracycline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and UV spectroscopy, and stringent control of related substances and residual solvents. Certificates of Analysis (COA) confirming compliance with in-house pharmaceutical-grade specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment away from direct light exposure to maintain stability and potency.

Specification

Item	Specification
Appearance	Yellow to yellowish-brown crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.