Description

1-(Ethoxycarbonyloxymethyl)-5-Fluorouracil is a fluoropyrimidine derivative and a key intermediate in the synthesis of advanced pharmaceutical compounds. This compound is valued for its role in creating prodrugs and modified nucleosides with targeted therapeutic effects. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of oncology and antiviral treatments.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel fluorouracil-based prodrugs and anticancer agents.
• Oncology Research: Used in preclinical and research settings to develop and study new chemotherapeutic compounds targeting DNA synthesis.
• Antiviral Drug Development: Serves as a precursor in the creation of nucleoside analogs with potential antiviral activity.
• Biochemical Research: Employed in studies investigating enzyme inhibition, cell proliferation, and metabolic pathways.
• Custom Synthesis: Supplied to fine chemical manufacturers for the custom synthesis of specialized active pharmaceutical ingredients (APIs).

Basic Information

Product Name	1-(Ethoxycarbonyloxymethyl)-5-Fluorouracil
CAS No.	106206-96-6
Molecular Formula	C9H11FN2O5
Molecular Weight	246.19 g/mol
Synonyms	5-Fluorouracil-1-ylmethoxycarbonyl ethyl ester; Ethyl 5-fluoro-1H-pyrimidine-2,4-dione-1-acetate; 1-Carbethoxymethyl-5-fluorouracil; 5-Fluoro-1-(ethoxycarbonylmethyl)uracil; 1-(Ethoxycarbonylmethyl)-5-fluorouracil; 5-FU-1-CH2-O-CO-O-Et; EC-1
EINECS	Contact for details

Quality Control

Our 1-(Ethoxycarbonyloxymethyl)-5-Fluorouracil is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.