Description

Cholan-24-Oic Acid, 3,6-Dihydroxy-, Ethyl Ester, (3A,5B,6A)- is a high-purity, synthetically derived bile acid derivative, specifically the ethyl ester of hyodeoxycholic acid. This compound is a critical intermediate in the synthesis of more complex pharmaceutical agents and biochemical research tools. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers for developing therapeutic compounds and reference standards.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel therapeutic agents targeting metabolic and liver-related disorders.
• Biochemical Research: Used as a reference standard or precursor in studies involving bile acid metabolism, receptor binding, and signaling pathways.
• Chiral Synthesis: Serves as a valuable chiral starting material or resolving agent in asymmetric synthesis due to its defined stereochemistry.
• API Development: Employed in the research and development of Active Pharmaceutical Ingredients (APIs) derived from bile acid scaffolds.
• Diagnostic Reagents: Potential use in the formulation of calibration standards for clinical diagnostic assays measuring bile acid profiles.

Basic Information

Product Name	Cholan-24-Oic Acid, 3,6-Dihydroxy-, Ethyl Ester, (3A,5B,6A)-
CAS No.	105660-11-5
Molecular Formula	C₂₆H₄₄O₄
Molecular Weight	420.63 g/mol
Synonyms	Ethyl Hyodeoxycholate; 3α,6α-Dihydroxy-5β-cholan-24-oic Acid Ethyl Ester; Hyodeoxycholic Acid Ethyl Ester; (3α,5β,6α)-3,6-Dihydroxycholan-24-oic Acid Ethyl Ester; 5β-Cholan-24-oic Acid, 3,6-dihydroxy-, Ethyl Ester, (3α,6α)-; Ethyl 3α,6α-dihydroxy-5β-cholan-24-oate
EINECS	Contact for details

Quality Control

Our Cholan-24-Oic Acid, 3,6-Dihydroxy-, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic methods (IR, NMR) for structural confirmation, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.