Description

Endoglyceroceramidase is a highly specific enzyme that catalyzes the hydrolysis of the glycosidic linkage in glycosphingolipids, particularly targeting the internal glycosidic bonds of complex glycolipids. This precise catalytic activity makes it an indispensable tool for structural analysis and research in lipid biochemistry and cell biology. It is primarily utilized by researchers and professionals in the pharmaceutical, biotechnology, and diagnostic sectors for glycan analysis, biomarker discovery, and the study of sphingolipid metabolism and related diseases.

Application

• Glycosphingolipid Structural Analysis: Essential for cleaving and sequencing complex glycan chains on ceramides to determine structure.
• Biomarker Research: Used to process and analyze glycosphingolipids from biological samples for the discovery of disease-specific markers.
• Cell Membrane Biology Studies: Employed to selectively modify cell surface glycosphingolipids to study their function in cell signaling and adhesion.
• Enzymology & Inhibitor Screening: Serves as a target enzyme in assays designed to discover and evaluate potential therapeutic inhibitors.
• Diagnostic Kit Development: A key component in the development of enzymatic assay kits for the detection of specific glycolipid-related disorders.
• Pharmaceutical R&D: Used in the research and development of therapies targeting lysosomal storage diseases and other metabolic disorders.

Basic Information

Product Name	Endoglyceroceramidase
CAS No.	105503-61-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Endoglycoceramidase; EGCase; Glycosphingolipid ceramide glycanase; Glycolipid ceramide deacylase; EC 3.2.1.123; Rhodococcus endoglycoceramidase; Endo-glycoceramidase
EINECS	Contact for details

Quality Control

Our Endoglyceroceramidase is produced and tested under stringent quality management systems. Each batch undergoes rigorous analytical testing to ensure high specific activity, purity, and functional consistency. A comprehensive Certificate of Analysis (COA) detailing assay results, purity, and stability is provided with every shipment to guarantee it meets the exacting standards required for research and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Activity)	Conforms (Enzymatic Assay)
Specific Activity	≥ [Value] units/mg protein
Purity (SDS-PAGE)	≥ 90%
Protein Content (Bradford)	Reported on COA
Endotoxin Level (LAL)	< 1.0 EU/µg
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.