Description

1,2-Di-o-(9Z-Octadecenyl)-Sn-Glycero-3-Phosphocholine is a high-purity synthetic phospholipid, specifically a phosphatidylcholine derivative with defined oleyl (C18:1) chains at the sn-1 and sn-2 positions. This compound is critical for creating stable, well-defined lipid bilayers and vesicles, offering superior consistency for advanced research and formulation development. It is an essential material for scientists and manufacturers in the life sciences, pharmaceutical development, and advanced material science sectors.

Application

• Liposome & Nanoparticle Formulation: A key structural lipid for constructing drug delivery vehicles, including liposomes, niosomes, and solid lipid nanoparticles (SLNs) for targeted therapeutic delivery.
• Biomembrane & Model System Research: Used to create defined artificial membranes (e.g., supported lipid bilayers, vesicles) for studying membrane biophysics, protein-lipid interactions, and cellular processes.
• Pharmaceutical Excipient: Serves as a functional excipient in advanced parenteral formulations to enhance drug solubility, stability, and bioavailability.
• Diagnostic Reagent Development: Employed in the manufacture of diagnostic kits and assays that utilize liposome-based signal amplification or cell membrane mimics.
• Cosmetic & Dermal Delivery Systems: A component in high-end cosmetic formulations for creating nanocarriers that improve the penetration and efficacy of active ingredients.
• Biophysical & Analytical Standards: Provides a pure, characterized standard for analytical methods such as HPLC, MS, and NMR in lipidomics research and quality control laboratories.

Basic Information

Product Name	1,2-Di-o-(9Z-Octadecenyl)-Sn-Glycero-3-Phosphocholine
CAS No.	105370-99-8
Molecular Formula	C46H90NO8P
Molecular Weight	816.18 g/mol
Synonyms	1,2-Dioleoyl-sn-glycero-3-phosphocholine (DOPC); (9Z,9'Z)-1,2-Bis(octadec-9-enoyl)-sn-glycero-3-phosphocholine; PC(18:1/18:1); DOPC (1,2-dioleoyl-sn-glycero-3-phosphocholine); L-α-Phosphatidylcholine, dioleoyl; Dioleoylphosphatidylcholine; 1,2-Di-(cis-9-octadecenoyl)-sn-glycero-3-phosphocholine
EINECS	Contact for details

Quality Control

Our 1,2-Di-o-(9Z-Octadecenyl)-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements of research and pharmaceutical applications. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. The product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to avoid condensation.

Specification

Item	Specification
Appearance	White to off-white waxy solid or viscous liquid
Identification (HPLC/MS)	Complies
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Peroxide Value	≤ 3.0 meq/kg
Solvent Residue (GC)	Complies with ICH limits
Phase Transition Temperature (DSC)	Approx. -20°C to -15°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.