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1,2-Dioctanoyl-Sn-Glycero-3-Phosphoinositol CAS NO 105172-95-0


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CAS No.:105172-95-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,2-Dioctanoyl-Sn-Glycero-3-Phosphoinositol is a synthetic, chemically defined phospholipid derivative, specifically a phosphoinositol analog with defined acyl chains. This compound is critical for research and development in lipid biochemistry and cell signaling pathways due to its role as a precursor or intermediate in the study of phosphoinositide metabolism. It is primarily utilized by pharmaceutical researchers, biochemical manufacturers, and academic institutions focused on membrane biology, drug discovery, and the synthesis of complex lipid standards.

Application

  • Biochemical Research: As a key intermediate or standard in the study of inositol phospholipid signaling pathways and second messenger systems.
  • Pharmaceutical Development: Used in the synthesis of novel drug candidates targeting lipid kinases, phosphatases, and related enzymes.
  • Liposome & Drug Delivery Systems: A component for creating specialized liposomal formulations to enhance drug targeting and cellular uptake.
  • Diagnostic Reagent Manufacturing: Serves as a raw material in producing assay kits for detecting and quantifying specific lipid metabolites.
  • Cell Biology Studies: Employed in experiments to investigate membrane dynamics, protein-lipid interactions, and cellular trafficking.
  • Enzyme Substrate: Acts as a substrate for in vitro assays of phospholipase and other lipid-modifying enzymes.

Basic Information

Product Name 1,2-Dioctanoyl-Sn-Glycero-3-Phosphoinositol
CAS No. 105172-95-0
Molecular Formula C29H53O13P
Molecular Weight 640.70 g/mol
Synonyms 1,2-Di-O-octanoyl-sn-glycero-3-phospho-(1D-myo-inositol); PI(8:0/8:0); 1,2-Dioctanoylphosphatidylinositol; sn-Glycero-3-phosphoinositol 1,2-dioctanoate; DOPI; 1,2-Di-C8:0 PI; Phosphatidylinositol diC8; 3-sn-Phosphatidyl-1D-myo-inositol 1,2-dioctanoate
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Quality Control

Our 1,2-Dioctanoyl-Sn-Glycero-3-Phosphoinositol is produced under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to rigorous internal quality standards to meet the demands of pharmaceutical and biochemical research. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. The material is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to exclude moisture. For long-term storage, desiccants are recommended.

Specification

Item Specification
Appearance White to off-white solid or waxy solid
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 95.0%
Water Content (KF) ≤ 2.0%
Solvent Residue (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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