Description

Alpha,β-Methyleneadenosine 5'-Diphosphate Sodium Salt is a chemically modified, non-hydrolyzable analog of adenosine diphosphate (ADP). This compound is of significant value in biochemical and pharmacological research as a potent and selective antagonist of P2Y purinergic receptors. It is primarily utilized by researchers and developers in the life sciences sector for studying nucleotide signaling pathways, enzyme kinetics, and as a critical tool in cardiovascular and neurological research applications.

Application

• P2Y Receptor Research: Acts as a selective antagonist for P2Y1, P2Y12, and P2Y13 receptor subtypes, crucial for studying platelet aggregation and thrombosis.
• Enzyme Inhibition Studies: Used as a non-hydrolyzable competitive inhibitor for ATP/ADP-dependent enzymes like kinases and synthases.
• Cardiovascular Pharmacology: A key tool compound in the development and screening of novel antiplatelet and antithrombotic agents.
• Neurological Research: Investigates the role of purinergic signaling in neuroinflammation, pain perception, and neurodegenerative diseases.
• Biochemical Assay Development: Serves as a standard or control in high-throughput screening (HTS) assays for drug discovery platforms.
• Cell Signaling Pathway Analysis: Used to elucidate the mechanisms of extracellular nucleotide signaling in various cell types.

Basic Information

Product Name	Alpha,β-Methyleneadenosine 5'-Diphosphate Sodium Salt
CAS No.	104835-70-3
Molecular Formula	C11H13N5O9P2Na2
Molecular Weight	483.17 g/mol
Synonyms	α,β-Methylene-ADP sodium salt; AOPCP sodium salt; Adenosine 5'-(α,β-methylene)diphosphate sodium salt; AMPCP sodium salt; Ap(CH2)ppNa2; P1,P2-Di(adenosine-5')-α,β-methylene diphosphate sodium salt; ARC 69931MX (analog); MRS 2179 (related compound)
EINECS	Contact for details

Quality Control

Our Alpha,β-Methyleneadenosine 5'-Diphosphate Sodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing purity, identity, and impurity profiles to ensure compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Heavy Metals	≤ 20 ppm
Solubility	Soluble in water, slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.