Description

Geranylgeranyl Diphosphate, Trisammonium Salt is a critical biosynthetic intermediate in the isoprenoid pathway, serving as the direct precursor for the synthesis of geranylgeranylated proteins and a wide range of diterpenoids. Its high purity and stability in salt form make it an essential reagent for enzymatic studies, metabolic pathway research, and the in vitro production of complex natural products. This compound is primarily utilized by research institutions, pharmaceutical developers, and biotechnology companies focused on cancer research, cardiovascular disease, and metabolic disorders, where protein prenylation plays a key regulatory role.

Application

• Enzymology & Biochemistry Research: Essential substrate for studies involving protein geranylgeranyltransferases (GGTases) and other prenyltransferases.
• Drug Discovery & Development: Used in high-throughput screening assays to identify and characterize inhibitors of protein prenylation, a target for anticancer and anti-parasitic therapies.
• In Vitro Synthesis: Key building block for the enzymatic synthesis of diterpenoids, carotenoids, and other isoprenoid compounds in biocatalytic processes.
• Cell Signaling Studies: Investigates the role of geranylgeranylated proteins (e.g., Rho, Rac GTPases) in cell proliferation, differentiation, and oncogenic transformation.
• Metabolic Pathway Analysis: Used to trace and quantify flux through the mevalonate pathway in metabolic engineering and systems biology.
• Reference Standard: Serves as a high-purity analytical standard for LC-MS, HPLC, and other chromatographic methods in quality control laboratories.

Basic Information

Product Name	Geranylgeranyl Diphosphate, Trisammonium Salt
CAS No.	104715-21-1
Molecular Formula	C20H44N3O7P2
Molecular Weight	515.52 g/mol
Synonyms	GGPP Trisammonium Salt; (all-E)-Geranylgeranyl Diphosphate Trisammonium Salt; Geranylgeranyl Pyrophosphate Trisammonium Salt; Farnesyl Diphosphate Homolog Tris Salt; (2E,6E,10E)-Geranylgeranyl Diphosphate Trisammonium Salt; Prenyl Diphosphate C20; GGPP (NH4)3; All-trans-Geranylgeranyl Diphosphate Trisammonium Salt
EINECS	Contact for details

Quality Control

Our Geranylgeranyl Diphosphate, Trisammonium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry for identity verification, to ensure it meets the high standards required for sensitive biochemical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated under an inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid or lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Assay (Enzymatic/UV)	≥ 90% (by weight)
Water Content (KF)	≤ 5.0 %
Solubility	Soluble in water, buffer solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.