Description

1-o-Octadecyl-2-Oleoyl-Sn-Glycero-3-Phospho-(n-Palmitoyl)Ethanolamine is a high-purity, synthetic phospholipid derivative, specifically a phosphatidylethanolamine (PE) analog. This compound is a critical component for advanced research and formulation in lipid-based delivery systems, offering a defined and reproducible chemical structure. It is essential for scientists and manufacturers in the pharmaceutical and biotechnology sectors who require precise lipid components for developing liposomes, lipid nanoparticles (LNPs), and other complex biomimetic membranes.

Application

• Liposome and Lipid Nanoparticle (LNP) Formulation: A key structural lipid for creating stable, targeted drug delivery vehicles for mRNA, siRNA, and small molecule therapeutics.
• Biomembrane Research: Used as a model membrane component in biophysical studies to investigate membrane fluidity, fusion, and protein-lipid interactions.
• Cell Culture and Transfection Reagents: Incorporated into lipid mixtures to enhance the efficiency of introducing nucleic acids into cells in vitro.
• Diagnostic Reagent Development: Serves as a functionalized lipid anchor for coupling targeting ligands or fluorescent probes in diagnostic assays.
• Cosmetic and Dermal Delivery Systems: Employed in the formulation of advanced cosmetic products for improved skin penetration and stabilization of active ingredients.

Basic Information

Product Name	1-o-Octadecyl-2-Oleoyl-Sn-Glycero-3-Phospho-(n-Palmitoyl)Ethanolamine
CAS No.	104672-13-1
Molecular Formula	C75H146NO8P
Molecular Weight	1188.96 g/mol
Synonyms	1-Stearyl-2-Oleoyl-sn-glycero-3-phospho-N-palmitoylethanolamine; SOPE-PE; N-Palmitoyl-1-stearyl-2-oleoyl-sn-glycero-3-phosphoethanolamine; 1-Octadecyl-2-oleoyl-sn-glycero-3-phosphoethanolamine-N-palmitoyl; PE-Ceramide analog; Synthetic Phosphatidylethanolamine Derivative; DSPE-PE Analog
EINECS	Contact for details

Quality Control

Every batch of our phospholipids is produced under strict quality management and undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from techniques such as NMR, HPLC, and MS. Our manufacturing process adheres to cGMP guidelines where applicable, supporting its use in pre-clinical and research-grade pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the product to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white waxy solid
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solvent Residue (GC)	Meets ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.