Description

Z-Phe-Leu-Glu-Pna CAS NO 104634-10-8 is a synthetic peptide substrate, specifically designed as a chromogenic compound for enzymatic activity assays. This product is critical for researchers and quality control laboratories requiring precise, reliable, and reproducible results in protease and peptidase studies. It is primarily utilized in the pharmaceutical, biotechnology, and life science research sectors for drug discovery, enzyme characterization, and biochemical pathway analysis.

Application

• Protease & Peptidase Activity Assays: Serves as a specific chromogenic substrate for measuring the catalytic activity of various proteolytic enzymes.
• Drug Discovery & Screening: Used in high-throughput screening (HTS) platforms to identify and characterize potential protease inhibitors as therapeutic candidates.
• Biochemical Research: Essential for studying enzyme kinetics, substrate specificity, and inhibition mechanisms in academic and industrial R&D.
• Quality Control in Biologics: Employed in the QC testing of biopharmaceuticals to monitor and validate the activity of enzyme-based products or processes.
• Diagnostic Reagent Development: Acts as a key component in developing in-vitro diagnostic kits for detecting specific protease activities linked to diseases.

Basic Information

Product Name	Z-Phe-Leu-Glu-Pna
CAS No.	104634-10-8
Molecular Formula	C31H39N5O8
Molecular Weight	609.68 g/mol
Synonyms	Z-Phe-Leu-Glu-pNA; Benzyloxycarbonyl-Phenylalanyl-Leucyl-Glutamic Acid p-Nitroanilide; N-CBZ-Phe-Leu-Glu-pNA; CBZ-Phe-Leu-Glu-p-Nitroanilide; Substrate for Glutamyl Endopeptidase; Chromogenic Substrate for Protease; Protease Substrate Z-F-L-E-pNA; Z-F-L-E-pNA
EINECS	Contact for details

Quality Control

Every batch of Z-Phe-Leu-Glu-Pna is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with high-purity standards suitable for research and diagnostic applications. A detailed Certificate of Analysis (COA), including HPLC purity, identity confirmation (IR, MS), and impurity profile, is provided with each shipment to guarantee reproducible performance and reliability in your assays.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.