Description

3,5,9-Trioxa-4-Phosphahexacosan-1-Aminium,7-(Acetyloxy)-4-Hydroxy-N,N,n-Trimethyl-10-Oxo-,Innersalt,4-Oxide,(R)-(9] is a complex, high-purity zwitterionic phospholipid derivative with a specific stereochemistry. This compound is valued for its unique amphiphilic structure, which makes it a critical intermediate in advanced pharmaceutical and biochemical research. It is primarily sought by R&D teams and process chemists in the pharmaceutical, biotechnology, and specialty chemical sectors for applications in drug delivery systems, lipid nanoparticle formulation, and as a building block for novel surfactants.

Application

• Lipid Nanoparticle (LNP) Formulation: A key synthetic intermediate in the production of ionizable cationic lipids used for mRNA and siRNA delivery.
• Pharmaceutical Intermediates: Serves as a crucial building block for the synthesis of advanced phospholipid-based active pharmaceutical ingredients (APIs) and prodrugs.
• Biochemical Research: Used in membrane biophysics studies and the development of synthetic cell membranes or liposomes with tailored surface properties.
• Specialty Surfactants: Acts as a precursor for synthesizing high-performance, biocompatible surfactants and emulsifiers for cosmetic and agrochemical formulations.
• Diagnostic Reagents: Potential use in the development of contrast agents or fluorescent probes for medical imaging and diagnostic assays.

Basic Information

Product Name	3,5,9-Trioxa-4-Phosphahexacosan-1-Aminium,7-(Acetyloxy)-4-Hydroxy-N,N,n-Trimethyl-10-Oxo-,Innersalt,4-Oxide,(R)-(9]
CAS No.	104585-73-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(R)-ALC-0315; ALC-0315 (R-enantiomer); ((4-hydroxybutyl)azanediyl)bis(hexane-6,1-diyl) bis(2-hexyldecanoate) (common name for related ionizable lipid); Ionizable Cationic Lipid Intermediate; SM-102 related compound; Phospholipid Derivative; Zwitterionic Phospholipid; Aminium Phosphatide Inner Salt
EINECS	Contact for details

Quality Control

Our 3,5,9-Trioxa-4-Phosphahexacosan-1-Aminium derivative is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid or viscous liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% (R-enantiomer)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.