Description

n-Formyl-Methionylleucyl-Phenylalanyl-N(Epsilon)-(2-(4-Azidosalicylamido)Ethyl-1,3'-Dithiopropionyl)Lysine is a specialized, high-purity synthetic peptide derivative designed for advanced biochemical research and development. This compound is engineered as a critical tool for photoaffinity labeling and cross-linking studies, enabling the precise mapping of protein-protein interactions and binding sites. It is essential for researchers and developers in pharmaceutical discovery, proteomics, and structural biology who require reliable, well-characterized probes for mechanistic studies.

Application

• Photoaffinity Labeling Probe: A key reagent for covalently tagging and identifying protein binding partners and active sites upon UV light activation.
• Bioconjugation & Cross-linking: Used to create stable covalent linkages between biomolecules for studying complex interactions or constructing targeted delivery systems.
• Proteomics Research: Facilitates the isolation and analysis of specific protein complexes from biological mixtures.
• Drug Discovery Target Validation: Employed to confirm and characterize the binding of potential drug candidates to their intended biological targets.
• Enzyme Mechanism Studies: Helps elucidate the structure and function of enzyme active sites and substrate interactions.
• Development of Diagnostic Assays: Serves as a component in the development of sensitive assays for detecting specific proteins or antibodies.

Basic Information

Item	Details
Product Name	n-Formyl-Methionylleucyl-Phenylalanyl-N(Epsilon)-(2-(4-Azidosalicylamido)Ethyl-1,3'-Dithiopropionyl)Lysine
CAS No.	104234-99-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	N-Formyl-Met-Leu-Phe-Lys(Nε-[2-(4-azidosalicylamido)ethyl-1,3'-dithiopropionyl]); fMLFK(SASD); Formyl-Met-Leu-Phe-Lys(SASD); Photoactivatable fMLP derivative; SASD-conjugated fMLFK peptide; N-Formylmethionylleucylphenylalanyl-N6-[2-[4-azido-2-hydroxybenzamido]ethyl-dithiodipropionamido]lysine; Azidosalicylamidoethyl-dithiopropionyl-fMLFK
EINECS	Contact for details

Quality Control

Our n-Formyl-Methionylleucyl-Phenylalanyl-N(Epsilon)-(2-(4-Azidosalicylamido)Ethyl-1,3'-Dithiopropionyl)Lysine is manufactured under strict quality systems to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, mass spectrometry for identity confirmation, and functional activity testing. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and maintain stability. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated at -80°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Functional Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.