Description

Le(Y)-Active Trifucosylnonaosylceramide is a complex, high-purity glycosphingolipid, specifically a ceramide bearing a branched nonasaccharide chain with three terminal fucose residues. This compound is a critical research-grade biochemical for investigating cell surface recognition, signal transduction, and carbohydrate-protein interactions. It is essential for researchers and developers in the fields of glycobiology, immunology, and oncology, serving as a standard, probe, or intermediate in the study of blood group antigens, cancer biomarkers, and host-pathogen interactions.

Application

• Glycobiology Research: Used as a reference standard or substrate to study the biosynthesis, function, and catabolism of complex glycosphingolipids.
• Immunological Studies: Employed in assays to investigate immune cell recognition, antigen presentation, and the role of glycolipids in autoimmune diseases.
• Cancer Biomarker Research: Serves as a key molecule for exploring the expression and role of Lewis Y (Ley) and related antigens in tumor progression and metastasis.
• Diagnostic Development: Acts as a critical coating antigen or capture molecule in the development of immunoassays and biosensors for disease detection.
• Drug Discovery: Utilized as a target or tool compound in screening programs aimed at developing therapeutics that modulate carbohydrate-mediated cell adhesion.
• Biochemical Reagent: Functions as a high-purity intermediate or building block for the chemical or enzymatic synthesis of more complex glycoconjugates.

Basic Information

Product Name	Le(Y)-Active Trifucosylnonaosylceramide
CAS No.	104200-12-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Ley-Active Glycolipid; Trifucosylnonaosylceramide; Lewis Y antigen ceramide; Fucα1-2Galβ1-4[Fucα1-3]GlcNAcβ1-3Galβ1-4Glcβ1-1Cer (with additional fucose); Blood group Lewis Y glycosphingolipid; Ley Ceramide; Glycolipid Ley
EINECS	Contact for details

Quality Control

Our Le(Y)-Active Trifucosylnonaosylceramide is manufactured under controlled conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes rigorous analytical characterization using techniques such as HPLC, MS, and NMR to confirm identity, purity, and structural integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Biological Activity (ELISA/Binding)	Conforms to reference

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.