Description

1-Hexadecanoyl-2-(1-Pyrenehexanoyl)-Sn-Glycero-3-Phosphocholine is a synthetic, fluorescently labeled phospholipid, specifically a phosphatidylcholine analog, widely used as a critical molecular probe in biophysical and cell biology research. Its core value lies in the incorporation of a pyrene fluorophore, which enables advanced studies of membrane dynamics, lipid trafficking, and protein-lipid interactions through techniques like fluorescence resonance energy transfer (FRET). This high-purity compound is essential for researchers and manufacturers in the life sciences, pharmaceutical development, and diagnostic sectors requiring precise tools for lipid bilayer characterization and assay development.

Application

• Membrane Biophysics Research: As a fluorescent probe for studying lipid bilayer properties, phase transitions, fusion, and lateral diffusion.
• Cell Biology & Imaging: Visualizing and tracking cellular membranes, endocytosis, and intracellular lipid transport in live-cell assays.
• Lipoprotein & Vesicle Studies: Labeling lipoproteins, liposomes, and exosomes to monitor their formation, stability, and cellular uptake.
• Drug Delivery System Development: A tool for formulating and characterizing targeted lipid-based nanoparticle (LNP) delivery systems.
• Enzymology Assays: Serving as a substrate or inhibitor in studies involving phospholipases and other lipid-modifying enzymes.
• Diagnostic Kit Development: Used in the formulation of fluorescent standards and reagents for clinical diagnostic assays.

Basic Information

Product Name	1-Hexadecanoyl-2-(1-Pyrenehexanoyl)-Sn-Glycero-3-Phosphocholine
CAS No.	103625-33-8
Molecular Formula	C50H78NO9P
Molecular Weight	876.13 g/mol
Synonyms	Pyrene-PC; 1-Palmitoyl-2-(1-pyrenedecanoyl)-sn-glycero-3-phosphocholine; 1-Palmitoyl-2-(pyrenedecanoyl)-sn-glycero-3-phosphocholine; 16:0-06:0 Pyrene PC; β-Py-C10-HPC; Fluorescent Phosphatidylcholine; Pyrene-labeled Phosphatidylcholine; 1-Hexadecanoyl-2-(1-pyrenebutanoyl)-sn-glycero-3-phosphocholine (related analog)
EINECS	Contact for details

Quality Control

Our 1-Hexadecanoyl-2-(1-Pyrenehexanoyl)-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high performance in sensitive applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, spectroscopic identification, and functional validation in standard assay formats. Certificates of Analysis (COA) detailing purity, identity, and specific performance characteristics are provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This compound is hygroscopic (moisture-sensitive) and light-sensitive. For long-term stability, store desiccated. Allow the vial to equilibrate to room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	Yellow to orange solid or film
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 98%
Fluorescence Properties	Ex/Em ~342/376 nm (monomer)
Solubility	Chloroform, Methanol, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.