Description

D-Luciferin Sodium Salt is a high-purity, water-soluble derivative of luciferin, the essential substrate for bioluminescence reactions. This compound is critical for enabling sensitive, real-time detection and quantification of biological processes in live cells and organisms. It is primarily utilized by researchers and developers in the life sciences, pharmaceutical, and biotechnology industries for applications such as in vivo imaging, high-throughput screening, and gene expression analysis. D-Luciferin Sodium Salt CAS NO 103404-75-7 offers consistent performance and reliable results for demanding experimental workflows.

Application

• Bioluminescence Imaging (BLI): The standard substrate for non-invasive, real-time monitoring of tumor growth, metastasis, and treatment efficacy in small animal models.
• Reporter Gene Assays: Used with firefly luciferase (Fluc) genes to measure promoter activity, gene expression levels, and cellular signaling pathways.
• High-Throughput Screening (HTS): Enables rapid, sensitive detection in cell-based assays for drug discovery and toxicology studies.
• ATP Detection & Cell Viability Assays: Serves as a key component in kits for quantifying cellular ATP levels, a direct indicator of cell health and metabolic activity.
• Microbial Detection: Employed in systems engineered to use luciferase as a reporter for detecting specific bacteria or monitoring microbial contamination.
• Molecular Diagnostics Development: Used in the research and development of novel diagnostic platforms leveraging bioluminescent signals.

Basic Information

Product Name	D-Luciferin Sodium Salt
CAS No.	103404-75-7
Molecular Formula	C11H7N2NaO3S2
Molecular Weight	302.30 g/mol
Synonyms	D-(-)-Luciferin Sodium Salt; Firefly Luciferin Sodium Salt; Beetle Luciferin Sodium Salt; (4S)-4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic Acid Sodium Salt; D-Luciferin, Sodium Salt; Sodium D-Luciferin; Luciferin, Sodium Salt; LH2-Na
EINECS	Contact for details

Quality Control

Our D-Luciferin Sodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for moisture and endotoxin levels where applicable. A Certificate of Analysis (COA) detailing all specifications and test results is provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤5.0%
Bioluminescent Activity	Passes functional assay
Solubility (in water)	Clear, yellow solution at 10 mg/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.