Description

(Tyr0)-Fibrinopeptide A is a synthetic peptide analog of the natural fibrinopeptide A sequence, modified by the absence of the tyrosine residue. This compound is a critical research tool for studying the mechanisms of blood coagulation and fibrinolysis. It is primarily utilized by biochemists and pharmaceutical researchers in academic, diagnostic, and drug discovery laboratories focused on cardiovascular disease, thrombosis, and hemostasis.

Application

• Biochemical Research: Used as a specific substrate or inhibitor in enzymatic assays to study thrombin activity and kinetics.
• Diagnostic Development: Serves as a key component in the development and calibration of in-vitro diagnostic tests for coagulation disorders.
• Drug Discovery: Employed in high-throughput screening (HTS) platforms to identify and evaluate novel anticoagulant or antithrombotic drug candidates.
• Mechanistic Studies: Facilitates research into the structure-function relationship of fibrinogen cleavage and fibrin formation.
• Quality Control: Acts as a reference standard for the quality assurance of related diagnostic reagents and biopharmaceuticals.

Basic Information

Product Name	(Tyr0)-Fibrinopeptide A
CAS No.	103226-11-5
Molecular Formula	C73H115N21O26S2
Molecular Weight	~1699.0 g/mol
Synonyms	Desulfated Fibrinopeptide A; Fibrinopeptide A (1-16), desulfato-[Tyr0]-; H-Tyr-Ala-Asp-Ser-Gly-Glu-Gly-Asp-Phe-Leu-Ala-Glu-Gly-Gly-Gly-Val-Arg-OH; FPA (Tyr0); Desulfato-fibrinopeptide A; [Tyr0]-FPA; Fibrinopeptide A analog (Tyr0); Thrombin substrate analog
EINECS	Contact for details

Quality Control

Our (Tyr0)-Fibrinopeptide A is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and MS for identity confirmation, to ensure it meets the high standards required for research and diagnostic applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.