Description

Ganglioside M1 Lactone CAS NO 103220-36-6 is a specific, high-purity derivative of the GM1 ganglioside, a crucial glycosphingolipid found in neural tissues. This compound is of significant value in biochemical and pharmaceutical research due to its role in studying cell signaling, membrane structure, and neurological processes. It is primarily needed by researchers and developers in the fields of neuroscience, immunology, and advanced drug discovery.

Application

• Neuroscience Research: As a key component of neuronal membranes, it is used to study cell-cell recognition, signal transduction, and the pathogenesis of neurological disorders.
• Biochemical Standard: Serves as a critical reference standard for the analysis and quantification of gangliosides in complex biological samples via HPLC, MS, or TLC.
• Pharmaceutical Development: Investigated for its potential therapeutic applications, including as a target or agent in treatments for neurodegenerative diseases like Alzheimer's and Parkinson's.
• Cell Biology Studies: Used to explore the role of gangliosides in cell growth, differentiation, and apoptosis, particularly in cancer research.
• Immunology Research: Applied in studies of immune modulation and the role of glycosphingolipids in immune cell function and autoimmune diseases.
• Diagnostic Reagent Development: Utilized in the development of diagnostic kits and assays for detecting ganglioside-related biomarkers.

Basic Information

Product Name	Ganglioside M1 Lactone
CAS No.	103220-36-6
Molecular Formula	C73H131N3O31
Molecular Weight	1562.8 g/mol
Synonyms	GM1 Lactone; Ganglioside GM1 Lactone; II3Neu5Ac-Gg4Cer Lactone; Monosialotetrahexosylganglioside Lactone; Lactonized GM1; N-Acetylneuraminosyl-GM1 Lactone; (2S,4S,5R,6R)-5-Acetamido-2-[(1R,2R)-3-[(2S,3R,4E)-3-[(β-D-Galactopyranosyl-(1→3)-2-acetamido-2-deoxy-β-D-galactopyranosyl-(1→4)-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl)oxy]-1-hydroxy-2-octadecenamido]-1-hydroxy-2-octadecyloxypropyl]-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2,4-dicarboxylic acid 2,6-lactone
EINECS	Contact for details

Quality Control

Our Ganglioside M1 Lactone is produced under stringent conditions to ensure the highest standards of purity and consistency, suitable for sensitive research applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via mass spectrometry. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical quality parameters.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store under an inert atmosphere. Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Biological Activity	To be determined per customer method

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.