Description

1,N6-Ethenoadenosine-3',5'-Cyclic Monophosphate Sodium Salt is a chemically modified, cell-permeable analog of the critical secondary messenger cyclic adenosine monophosphate (cAMP). This compound is engineered for enhanced stability and resistance to phosphodiesterase degradation, making it a powerful tool for sustained activation of protein kinase A (PKA) and related signaling pathways in cellular research. It is essential for researchers and developers in pharmacology, molecular biology, and biochemistry who require precise modulation of intracellular cAMP levels to study signal transduction, gene expression, and cellular function.

Application

• Biochemical Research: As a stable cAMP analog for investigating cAMP-dependent protein kinase (PKA) signaling cascades and downstream effects.
• Cell Biology Studies: For probing cellular processes such as metabolism, secretion, gene transcription, and ion channel regulation.
• Drug Discovery & Pharmacology: Used in high-throughput screening assays to identify and characterize novel therapeutics targeting the cAMP pathway.
• Signal Transduction Analysis: A key reagent for studying the role of cAMP in hormone action, neurotransmission, and immune response.
• Academic & Institutional Research: Fundamental tool for universities and research institutes exploring cellular communication mechanisms.

Basic Information

Product Name	1,N6-Ethenoadenosine-3',5'-Cyclic Monophosphate Sodium Salt
CAS No.	103213-51-0
Molecular Formula	C12H12N5NaO6P
Molecular Weight	384.22 g/mol
Synonyms	1,N6-Etheno-cAMP Sodium Salt; 1,N6-Ethenoadenosine 3',5'-cyclic monophosphate sodium salt; ε-cAMP Sodium Salt; Etheno-cAMP Na; 1,N6-Etheno-cyclic AMP sodium salt; Fluorescent cAMP analog sodium salt; Adenosine, 1,N6-etheno-3',5'-cyclic phosphate, sodium salt
EINECS	Contact for details

Quality Control

Our 1,N6-Ethenoadenosine-3',5'-Cyclic Monophosphate Sodium Salt is manufactured under strict quality systems suitable for research applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment to ensure traceability and meet the stringent requirements of academic and industrial research laboratories.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.