Description

Guanylyl-(2',5')-Guanosine, Ammonium salt is a chemically modified nucleotide derivative, specifically a dinucleoside monophosphate. This compound is a crucial biochemical tool and building block in oligonucleotide synthesis and research. It is primarily utilized by researchers and manufacturers in the fields of pharmaceutical development, molecular biology, and diagnostic reagent production. Its unique 2',5'-linkage makes it valuable for studying RNA structure, function, and for developing novel therapeutic agents.

Application

• Biochemical Research: As a substrate or intermediate in enzymatic studies and metabolic pathway analysis.
• Oligonucleotide Synthesis: Serving as a specialized phosphoramidite or solid-phase synthesis building block for non-canonical RNA analogs.
• Pharmaceutical R&D: Investigation and development of antisense oligonucleotides, siRNA, and other nucleic acid-based therapeutics.
• Diagnostic Reagents: Component in the manufacture of probes and kits for molecular diagnostics and virology.
• Enzyme Mechanism Studies: Used to study the activity and specificity of nucleotidyltransferases and ligases.
• Reference Standard: Acts as a high-purity analytical standard for quality control in related biopharmaceutical processes.

Basic Information

Product Name	Guanylyl-(2',5')-Guanosine, Ammonium salt
CAS No.	103213-36-1
Molecular Formula	C₂₀H₂₉N₁₀O₁₂P • xNH₃
Molecular Weight	Contact for details
Synonyms	G(2',5')G ammonium salt; 2',5'-GpG ammonium salt; P1-Guanosin-5'-yl P2-guanosin-2'-yl diphosphate ammonium salt; Guanosine-2',5'-bisphosphate ammonium salt (mixed isomers); Guanylyl-(2'-5')-guanosine ammonium salt; Dinucleoside monophosphate GpG (2',5') ammonium salt; 2',5'-Linked diguanylic acid ammonium salt
EINECS	Contact for details

Quality Control

Our Guanylyl-(2',5')-Guanosine, Ammonium salt is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We support research and GMP-grade requirements with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive). For long-term storage under inert atmosphere, please contact our technical team for specific recommendations. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.