Description

H-Gly-Arg-Pna CAS NO 103192-40-1 is a specialized peptide derivative, specifically a chromogenic substrate designed for enzymatic activity studies. This compound is critical for biochemical research and diagnostic assay development, providing a reliable and sensitive means to detect and quantify specific protease activity. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for drug discovery, enzyme characterization, and high-throughput screening applications.

Application

• Protease Enzyme Assays: Acts as a specific chromogenic substrate for the detection and kinetic analysis of trypsin-like serine proteases.
• Biochemical Research: Used in academic and industrial laboratories to study enzyme mechanisms, inhibition, and substrate specificity.
• Pharmaceutical Screening: Employed in high-throughput screening (HTS) platforms to identify and evaluate potential protease inhibitor drug candidates.
• Diagnostic Kit Development: Serves as a key component in the formulation of diagnostic tests and kits for clinical and research purposes.
• Quality Control in Bioprocessing: Used to monitor and ensure the activity and consistency of enzyme preparations used in manufacturing processes.

Basic Information

Product Name	H-Gly-Arg-Pna
CAS No.	103192-40-1
Molecular Formula	C15H23N7O4
Molecular Weight	365.39 g/mol
Synonyms	Gly-Arg-p-nitroanilide; Glycyl-L-arginine 4-nitroanilide; H-Gly-Arg-pNA; L-Glycyl-L-arginine 4-nitroanilide; GGR-pNA; Boc-Gly-Arg-pNA; Substrate for Trypsin; Chromogenic Trypsin Substrate
EINECS	Contact for details

Quality Control

Our H-Gly-Arg-Pna is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research and diagnostic applications. Each lot undergoes comprehensive analytical testing including HPLC for purity, identity confirmation by spectroscopic methods, and verification of biological activity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in water, DMSO
Biological Activity	Conforms to reference standard

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.