Description

Mevalonic Acid, R, Pyrophosphate is a key phosphorylated intermediate in the mevalonate pathway, essential for isoprenoid and sterol biosynthesis. Its high purity and stability are critical for ensuring the reliability of enzymatic and metabolic research. This compound is primarily required by researchers and manufacturers in the pharmaceutical, biotechnology, and nutraceutical sectors for biochemical studies, enzyme assays, and the development of metabolic pathway inhibitors.

Application

• Biochemical Research: Essential substrate for studying enzymes in the mevalonate pathway, such as mevalonate kinase and phosphomevalonate kinase.
• Pharmaceutical Development: Used in high-throughput screening assays to identify and characterize novel inhibitors targeting cholesterol biosynthesis and related metabolic disorders.
• Metabolic Pathway Analysis: A critical standard and reagent for tracing and quantifying metabolic flux in isoprenoid biosynthesis using LC-MS or NMR techniques.
• Enzyme Kinetics & Characterization: Serves as a precise substrate for determining kinetic parameters (Km, Vmax) and inhibition constants (Ki) of pathway enzymes.
• Reference Standard: Used as a certified reference material (CRM) for quality control and method validation in analytical laboratories.
• Nutraceutical Research: Applied in studies investigating the biosynthesis of coenzyme Q10, carotenoids, and other biologically active isoprenoids.

Basic Information

Product Name	Mevalonic Acid, R, Pyrophosphate
CAS No.	103025-21-4
Molecular Formula	C6H14O10P2
Molecular Weight	308.12 g/mol
Synonyms	(R)-Mevalonic Acid 5-Diphosphate; (R)-Mevalonic Acid 5-Pyrophosphate; (R)-Mevalonate 5-Diphosphate; (R)-Mevalonate 5-Pyrophosphate; (R)-5-Diphosphomevalonic Acid; (R)-5-Pyrophosphomevalonic Acid; (3R)-3,5-Dihydroxy-3-methylpentanoic Acid 5-Diphosphate; MVAPP
EINECS	Contact for details

Quality Control

Our Mevalonic Acid, R, Pyrophosphate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, IR), to ensure it meets the stringent requirements for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, desiccate. Allow the sealed container to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.