Description

5,12,20-Trihydroxy-6,8,14-Eicosatrienoic Acid is a specialized polyhydroxy fatty acid derivative with a unique conjugated triene structure. This compound is of significant interest in biochemical and pharmaceutical research due to its role as a potential bioactive lipid mediator and metabolic intermediate. It is primarily utilized by research institutions and development laboratories in the life sciences sector for advanced studies in lipidomics, inflammation pathways, and metabolic regulation.

Application

• Biochemical Research Standard: Used as a high-purity reference standard for analytical method development and validation in lipid analysis.
• Pharmaceutical R&D: Investigated as a potential lead compound or intermediate for novel therapeutic agents targeting inflammatory and metabolic disorders.
• Cell Signaling Studies: Employed in in-vitro studies to elucidate the role of hydroxy fatty acids in cellular signaling cascades and receptor interactions.
• Metabolic Pathway Analysis: Serves as a substrate or marker in enzymatic assays and metabolic flux studies related to eicosanoid and oxylipin biosynthesis.
• Academic Research: A key material for universities and research institutes conducting fundamental research on fatty acid biochemistry and oxidation products.
• Analytical Chemistry: Used to calibrate instruments (e.g., LC-MS, GC-MS) for the accurate identification and quantification of complex lipid species in biological samples.

Basic Information

Product Name	5,12,20-Trihydroxy-6,8,14-Eicosatrienoic Acid
CAS No.	102910-23-6
Molecular Formula	C₂₀H₃₂O₅
Molecular Weight	352.47 g/mol
Synonyms	5,12,20-TriHETE; (6E,8Z,14Z)-5,12,20-Trihydroxyicosa-6,8,14-trienoic acid; 5,12,20-Trihydroxyeicosatrienoic Acid; 5,12,20-THETA; 5,12,20-Trihydroxy-6,8,14-icosatrienoic acid; 20-Hydroxy-5,12-diHETE; 5,12,20-Trihydroxy-6,8,14-eicosatrienoic acid
EINECS	Contact for details

Quality Control

Our 5,12,20-Trihydroxy-6,8,14-Eicosatrienoic Acid is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for critical research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, generated using validated analytical methods such as HPLC and NMR. We are committed to supplying materials that meet the stringent requirements of pharmaceutical and analytical research standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. Due to its hygroscopic (moisture-sensitive) nature, the container must be sealed under dry conditions and allowed to equilibrate to room temperature before opening to prevent condensation and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.