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2'-Deoxyguanosine 3'-Monophosphate Sodium Salt CAS NO 102814-03-9


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CAS No.:102814-03-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2'-Deoxyguanosine 3'-Monophosphate Sodium Salt is a high-purity nucleotide building block essential for life science research and pharmaceutical development. This compound serves as a critical monomer for the chemical synthesis of oligonucleotides, enabling the creation of primers, probes, and therapeutic nucleic acids. It is primarily utilized by researchers and manufacturers in the fields of molecular biology, diagnostics, and the development of novel antiviral and anticancer agents.

Application

  • Oligonucleotide Synthesis: A fundamental phosphoramidite monomer for the solid-phase synthesis of DNA and RNA sequences.
  • Research Reagent: Used in enzymatic studies, as a substrate for kinases and polymerases, and in metabolic pathway research.
  • Diagnostic Development: Incorporated into probes and primers for PCR, sequencing, and other molecular diagnostic assays.
  • Pharmaceutical Intermediates: Serves as a key starting material for the production of nucleotide-based antiviral drugs (e.g., for hepatitis, HIV) and other therapeutic nucleic acids.
  • Biochemical Standards: Used as a reference standard in analytical laboratories for quality control and method validation.

Basic Information

Item Details
Product Name 2'-Deoxyguanosine 3'-Monophosphate Sodium Salt
CAS No. 102814-03-9
Molecular Formula C10H12N5Na2O7P
Molecular Weight 391.19 g/mol
Synonyms 2'-Deoxy-GMP Sodium Salt; dGMP Sodium Salt; Deoxyguanylic Acid Sodium Salt; Sodium 2'-Deoxyguanylate; 2'-Deoxyguanosine 5'-(Disodium Phosphate); Guanosine, 2'-deoxy-, 5'-(dihydrogen phosphate), disodium salt; dG-5'-MP Na2
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Quality Control

Our 2'-Deoxyguanosine 3'-Monophosphate Sodium Salt is manufactured under strict quality systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and stringent tests for residual solvents and endotoxins where required. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to prevent condensation.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms to reference standard
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 5.0%
pH (1% Solution) 6.0 - 8.0
Endotoxin (where specified) < 0.1 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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