Description

2'-Deoxyuridine-3'-Monophosphate Disodium Salt is a high-purity nucleotide derivative essential for biochemical and pharmaceutical research. This compound serves as a critical building block and intermediate in the synthesis of oligonucleotides and modified nucleic acids. It is primarily utilized by research institutions and pharmaceutical companies engaged in molecular biology, antiviral drug development, and diagnostic assay manufacturing.

Application

• Oligonucleotide Synthesis: A key phosphoramidite precursor for the solid-phase synthesis of DNA and RNA sequences.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving thymidylate synthase and other nucleotide metabolism enzymes.
• Antiviral Drug Development: Serves as an important intermediate in the research and production of nucleoside analog prodrugs.
• Diagnostic Reagents: Incorporated into probes and primers for molecular diagnostics, including PCR and sequencing applications.
• Cell Culture & Media: A component of specialized cell culture media for studying nucleotide metabolism and cell proliferation.
• Enzyme Kinetics: Employed in assays to study enzyme kinetics and mechanisms of action for drug discovery targets.

Basic Information

Product Name	2'-Deoxyuridine-3'-Monophosphate Disodium Salt
CAS No.	102783-59-5
Molecular Formula	C9H11N2Na2O8P
Molecular Weight	352.13 g/mol
Synonyms	dUMP Disodium Salt; 2'-Deoxyuridine 3'-Monophosphate Disodium Salt; Deoxyuridylic Acid Disodium Salt; 3'-dUMP Na2; Uridine, 2'-deoxy-, 3'-(dihydrogen phosphate), disodium salt; 2'-Deoxyuridine-3'-phosphate disodium; dU-3'-P Disodium Salt
EINECS	Contact for details

Quality Control

Our 2'-Deoxyuridine-3'-Monophosphate Disodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and stringent tests for residual solvents and endotoxins where applicable. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
pH (1% Solution)	6.5 - 8.5
Endotoxin (where specified)	< 0.1 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.